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Pregled bibliografske jedinice broj: 1218331

Synthesis and biological activity of amidino substituted benzimidazoles and benzothiazoles

Beč, Anja; Tomić, Teo; Racané, Livio; Persoons, Leentje; Daelemans, Dirk; Banjanac, Mihailo; Radovanović, Vedrana; Hranjec, Marijana
Synthesis and biological activity of amidino substituted benzimidazoles and benzothiazoles // BOOK OF ABSTRACTS 19th Ružička Days TODAY SCIENCE – TOMORROW INDUSTRY / Babić, Jurislav (ur.).
Osijek : Zagreb: Prehrambeno tehnološki fakultet Sveučilišta Josipa Jurja Strossmayera u Osijeku ; Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI), 2022. str. 110-110 (poster, međunarodna recenzija, sažetak, znanstveni)

CROSBI ID: 1218331 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Synthesis and biological activity of amidino substituted benzimidazoles and benzothiazoles

Autori
Beč, Anja ; Tomić, Teo ; Racané, Livio ; Persoons, Leentje ; Daelemans, Dirk ; Banjanac, Mihailo ; Radovanović, Vedrana ; Hranjec, Marijana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
BOOK OF ABSTRACTS 19th Ružička Days TODAY SCIENCE – TOMORROW INDUSTRY / Babić, Jurislav - Osijek : Zagreb : Prehrambeno tehnološki fakultet Sveučilišta Josipa Jurja Strossmayera u Osijeku ; Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI), 2022, 110-110

Skup
19. Ružičkini dani "Danas znanost - sutra industrija"

Mjesto i datum
Vukovar, Hrvatska, 21.09.2022. - 23.09.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
antiproliferative and antibacterial activity, benzimidazoles, benzothiazoles

Sažetak
Due to the great biological importance of benzimidazole and benzothiazole derived derivatives, nowadays there is still an increasing interest in medicinal and pharmaceutical chemistry for using this unavoidable structural motifs in the rational design of novel drugs. Suchlike derivatives display a broad spectrum of different biological features such as anticancer, antiviral, antioxidant, antibacterial, antifungal, antihistaminic, anti-inflammatory, etc. Amidines are structural parts of numerous biologically active compounds like many important medical and biochemical agents. By introduction of amidino functional groups at the termini of the molecule, the biological activity could be significantly improved because of interaction with an electronegatively charged biological molecule such as DNA. Herein we present the synthesis and biological evaluation of novel amidino substituted benzimidazole and benzothiazole derivatives substituted with 2-hydroxyphehyl ring in the position 2. All compounds were tested for their antiproliferative activity on several human cancer cells as well as for antibacterial activity in vitro.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA

Projekti:
HRZZ-IP-2018-01-4379 - Istraživanje antioksidativnog djelovanja benzazolskog skeleta u dizajnu novih antitumorskih agensa (AntioxPot) (Hranjec, Marijana, HRZZ - 2018-01) ( CroRIS)

Ustanove:
Tekstilno-tehnološki fakultet, Zagreb,
Fakultet kemijskog inženjerstva i tehnologije, Zagreb

Profili:

Avatar Url Mihailo Banjanac (autor)

Avatar Url Anja Beč (autor)

Avatar Url Marijana Hranjec (autor)

Avatar Url Livio Racane (autor)

Poveznice na cjeloviti tekst rada:

Pristup cjelovitom tekstu rada

Citiraj ovu publikaciju:

Beč, Anja; Tomić, Teo; Racané, Livio; Persoons, Leentje; Daelemans, Dirk; Banjanac, Mihailo; Radovanović, Vedrana; Hranjec, Marijana
Synthesis and biological activity of amidino substituted benzimidazoles and benzothiazoles // BOOK OF ABSTRACTS 19th Ružička Days TODAY SCIENCE – TOMORROW INDUSTRY / Babić, Jurislav (ur.).
Osijek : Zagreb: Prehrambeno tehnološki fakultet Sveučilišta Josipa Jurja Strossmayera u Osijeku ; Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI), 2022. str. 110-110 (poster, međunarodna recenzija, sažetak, znanstveni)
Beč, A., Tomić, T., Racané, L., Persoons, L., Daelemans, D., Banjanac, M., Radovanović, V. & Hranjec, M. (2022) Synthesis and biological activity of amidino substituted benzimidazoles and benzothiazoles. U: Babić, J. (ur.)BOOK OF ABSTRACTS 19th Ružička Days TODAY SCIENCE – TOMORROW INDUSTRY.
@article{article, author = {Be\v{c}, Anja and Tomi\'{c}, Teo and Racan\'{e}, Livio and Persoons, Leentje and Daelemans, Dirk and Banjanac, Mihailo and Radovanovi\'{c}, Vedrana and Hranjec, Marijana}, editor = {Babi\'{c}, J.}, year = {2022}, pages = {110-110}, keywords = {antiproliferative and antibacterial activity, benzimidazoles, benzothiazoles}, title = {Synthesis and biological activity of amidino substituted benzimidazoles and benzothiazoles}, keyword = {antiproliferative and antibacterial activity, benzimidazoles, benzothiazoles}, publisher = {Prehrambeno tehnolo\v{s}ki fakultet Sveu\v{c}ili\v{s}ta Josipa Jurja Strossmayera u Osijeku ; Hrvatsko dru\v{s}tvo kemijskih in\v{z}enjera i tehnologa (HDKI)}, publisherplace = {Vukovar, Hrvatska} }
@article{article, author = {Be\v{c}, Anja and Tomi\'{c}, Teo and Racan\'{e}, Livio and Persoons, Leentje and Daelemans, Dirk and Banjanac, Mihailo and Radovanovi\'{c}, Vedrana and Hranjec, Marijana}, editor = {Babi\'{c}, J.}, year = {2022}, pages = {110-110}, keywords = {antiproliferative and antibacterial activity, benzimidazoles, benzothiazoles}, title = {Synthesis and biological activity of amidino substituted benzimidazoles and benzothiazoles}, keyword = {antiproliferative and antibacterial activity, benzimidazoles, benzothiazoles}, publisher = {Prehrambeno tehnolo\v{s}ki fakultet Sveu\v{c}ili\v{s}ta Josipa Jurja Strossmayera u Osijeku ; Hrvatsko dru\v{s}tvo kemijskih in\v{z}enjera i tehnologa (HDKI)}, publisherplace = {Vukovar, Hrvatska} }

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