Pregled bibliografske jedinice broj: 1218225
Preferences of different polyphenol groups of P. spinosa L. flower extract toward organ bioaccumulation in in vivo model of absorption in C57BL/6 mice
Preferences of different polyphenol groups of P. spinosa L. flower extract toward organ bioaccumulation in in vivo model of absorption in C57BL/6 mice // Book of Abstracts of the Congress of the Croatian Society of Biochemistry and Molecular Biology “Crossroads in Life Sciences”, HDBMB
Lovran, Hrvatska, 2019. str. 96-96 (poster, domaća recenzija, sažetak, znanstveni)
CROSBI ID: 1218225 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Preferences of different polyphenol groups of P.
spinosa L. flower extract toward organ
bioaccumulation in in vivo model of absorption in
C57BL/6 mice
Autori
Landeka Jurčević, Irena ; Đikić, Domagoj ; Zorić, Zoran ; Balta, Vedran ; Fabijančić, Irena ; Dragović- Uzelac, Verica ; Padovan, Jasna
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Book of Abstracts of the Congress of the Croatian Society of Biochemistry and Molecular Biology “Crossroads in Life Sciences”, HDBMB
/ - , 2019, 96-96
ISBN
978-953-95551-7-5
Skup
Congress of the Croatian Society of Biochemistry and Molecular Biology "Crossroads in Life Sciences" (HDBMB2019)
Mjesto i datum
Lovran, Hrvatska, 25.09.2019. - 28.09.2019
Vrsta sudjelovanja
Poster
Vrsta recenzije
Domaća recenzija
Ključne riječi
bioavailability ; Prunus spinosa L. ; polyphenol compounds
Sažetak
Polyphenol (PPH) organ distribution may explicite their physiological efficacy. Water extract of blackthorn (Prunus spinosa L.) flower (PSE) was used to model the tissue distribution of PPH in C57BL/6 mice following oral acute and repeated (subchronic 28 days) administration of 25 mg/kg bw of total PPH. 32 individual PPH's were measured by UPLC-MS (15 min, 30 min, 1h, 3h, 6h, 24h in acute and 1st, 7th, 14th, 21th, 28th day in subchronic treatment).Highest present PPH in the PSE were not necessarily the highest bioavialable in the tissues. Repeated treatment increased the number of significantly higher PPHv Cmax/AUCalast, innn PSE treated animals vs. control, by +6% in the intestine, +45.5% in the liver. +16.0% in kidney and +32% in the brain. Intestine had preference for bioaccumulation of ferulloylquinic acid and kaempherol-pentoside, liver for kaempherol- pentosid and quercetin-3-O-rutinosid, kidney for ferullic acid and quercetin-rutinoside and brain bioacumullated quercetin-rhamnoside and quercetin- rutinoside.
Izvorni jezik
Engleski
Znanstvena područja
Biologija, Temeljne medicinske znanosti, Biotehnologija, Prehrambena tehnologija, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)
POVEZANOST RADA
Profili:
Irena Fabijančić
(autor)
Verica Dragović-Uzelac
(autor)
Vedran Balta
(autor)
Jasna Padovan
(autor)
Zoran Zorić
(autor)
Domagoj Đikić
(autor)
Irena Landeka Jurčević
(autor)