Naslov
DEVELOPMENT OF NEW COST-EFFECTIVE MICROFLUIDICS METHOD FOR CARNOSINE DETERMINATION IN DIETARY SUPPLEMENTS

Autori
Pukleš, Iva ; Sakač, Nikola ; Matasović, Brunislav ; Šarkanj, Bojan ; Vesigner, Ana ; Jozanović, Marija

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
19th Ružička Days TODAY SCIENCE – TOMORROW INDUSTRY Book of abstracts / Babić, Jurislav - Osijek, 2022, 43-43

Skup
19. Ružičkini dani "Danas znanost - sutra industrija"

Mjesto i datum
Vukovar, Hrvatska, 21.09.2022. - 23.09.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Carnosine ; C4D detector ; Dietary supplements ; Microchip capillary electrophoresi
(carnosine ; C4D detector ; dietary supplements ; microchip capillary electrophoresi)

Sažetak
Dipeptide L-carnosine is used in dietary supplements formulations to improve endurance during intense exercise. This report describes the new microchip electrophoresis (MCE) method to determine L-carnosine in dietary supplements samples. Capacitively coupled contactless conductivity detection (C4D) was employed as an alternative to expensive, timeconsuming, and complex detection methods commonly used for peptides detection. Detector response showed high linearity in the tested range of 2.5 – 25 µmol/L. The separation was rapid, owing to 73 s migration time of L-carnosine. The proposed microfluidic method showed great potential for further analysis of L-carnosine in dietary supplement samples.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Farmacija

POVEZANOST RADA