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Pregled bibliografske jedinice broj: 1214416

3T MRI signal intensity profiles and thicknesses of transient zones in human fetal brain at mid-gestation


Pogledić, Ivana; Schwartz, Ernst; Bobić-Rasonja, Mihaela; Mitter, Christian; Baltzer, Pascal; Gruber, Gerlinde Maria; Milković-Periša, Marija; Haberler, Christine; Bettelheim, Dieter; Kasprian, Gregor et al.
3T MRI signal intensity profiles and thicknesses of transient zones in human fetal brain at mid-gestation // European journal of paediatric neurology, 35 (2021), 67-73 doi:10.1016/j.ejpn.2021.09.014 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1214416 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
3T MRI signal intensity profiles and thicknesses of transient zones in human fetal brain at mid-gestation

Autori
Pogledić, Ivana ; Schwartz, Ernst ; Bobić-Rasonja, Mihaela ; Mitter, Christian ; Baltzer, Pascal ; Gruber, Gerlinde Maria ; Milković-Periša, Marija ; Haberler, Christine ; Bettelheim, Dieter ; Kasprian, Gregor ; Judaš, Miloš ; Prayer, Daniela ; Jovanov-Milošević, Nataša

Izvornik
European journal of paediatric neurology (1090-3798) 35 (2021); 67-73

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
malformations of cortical development ; subplate ; extracellular matrix ; postmortem MRI ; brain tissue shrinkage

Sažetak
In this study we compare temporal lobe (TL) signal intensity (SI) profiles, along with the average thicknesses of the transient zones obtained from postmortem MRI (pMRI) scans and corresponding histological slices, to the frontal lobe (FL) SI and zone thicknesses, in normal fetal brains. The purpose was to assess the synchronization of the corticogenetic processes in different brain lobes. Nine postmortem human fetal brains without cerebral pathologies, from 19 to 24 weeks of gestation (GW) were analyzed on T2-weighted 3T pMRI, at the coronal level of the thalamus and basal ganglia. The SI profiles of the transient zones in the TL correlate well spatially and temporally to the signal intensity profile of the FL. During the examined period, in the TL, the intermediate and subventricular zone are about the size of the subplate zone (SP), while the superficial SP demonstrates the highest signal intensity. The correlation of the SI profiles and the distributions of the transient zones in the two brain lobes, indicates a time-aligned histogenesis during this narrow time window. The 3TpMRI enables an assessment of the regularity of lamination patterns in the fetal telencephalic wall, upon comparative evaluation of sizes of the transient developmental zones and the SI profiles of different cortical regions. A knowledge of normal vs. abnormal transient lamination patterns and the SI profiles is a prerequisite for further advancement of the MR diagnostic tools needed for early detection of developmental brain pathologies prenatally, especially mild white matter injuries such as lesions of TL due to prenatal cytomegalovirus infections, or cortical malformations.

Izvorni jezik
Engleski



POVEZANOST RADA


Projekti:
--IP-2019-04-3182 - Moždani izvanstanični matriks u razvitku i perinatalnoj hipoksiji (BRAINECM) (Jovanov Milošević, Nataša) ( CroRIS)
--KK.01.1.1.01.0007 - Znanstveni centar izvrnosti - Eksperimentalna i klinička istraživanja hipoksijsko-ishemijskog oštećenja mozga u perinatalnoj i odrasloj dobi (ZCI - NEURO) (Judaš, Miloš) ( CroRIS)

Ustanove:
Medicinski fakultet, Zagreb,
Klinički bolnički centar Zagreb

Poveznice na cjeloviti tekst rada:

doi www.ejpn-journal.com

Citiraj ovu publikaciju:

Pogledić, Ivana; Schwartz, Ernst; Bobić-Rasonja, Mihaela; Mitter, Christian; Baltzer, Pascal; Gruber, Gerlinde Maria; Milković-Periša, Marija; Haberler, Christine; Bettelheim, Dieter; Kasprian, Gregor et al.
3T MRI signal intensity profiles and thicknesses of transient zones in human fetal brain at mid-gestation // European journal of paediatric neurology, 35 (2021), 67-73 doi:10.1016/j.ejpn.2021.09.014 (međunarodna recenzija, članak, znanstveni)
Pogledić, I., Schwartz, E., Bobić-Rasonja, M., Mitter, C., Baltzer, P., Gruber, G., Milković-Periša, M., Haberler, C., Bettelheim, D. & Kasprian, G. (2021) 3T MRI signal intensity profiles and thicknesses of transient zones in human fetal brain at mid-gestation. European journal of paediatric neurology, 35, 67-73 doi:10.1016/j.ejpn.2021.09.014.
@article{article, author = {Pogledi\'{c}, Ivana and Schwartz, Ernst and Bobi\'{c}-Rasonja, Mihaela and Mitter, Christian and Baltzer, Pascal and Gruber, Gerlinde Maria and Milkovi\'{c}-Peri\v{s}a, Marija and Haberler, Christine and Bettelheim, Dieter and Kasprian, Gregor and Juda\v{s}, Milo\v{s} and Prayer, Daniela and Jovanov-Milo\v{s}evi\'{c}, Nata\v{s}a}, year = {2021}, pages = {67-73}, DOI = {10.1016/j.ejpn.2021.09.014}, keywords = {malformations of cortical development, subplate, extracellular matrix, postmortem MRI, brain tissue shrinkage}, journal = {European journal of paediatric neurology}, doi = {10.1016/j.ejpn.2021.09.014}, volume = {35}, issn = {1090-3798}, title = {3T MRI signal intensity profiles and thicknesses of transient zones in human fetal brain at mid-gestation}, keyword = {malformations of cortical development, subplate, extracellular matrix, postmortem MRI, brain tissue shrinkage} }
@article{article, author = {Pogledi\'{c}, Ivana and Schwartz, Ernst and Bobi\'{c}-Rasonja, Mihaela and Mitter, Christian and Baltzer, Pascal and Gruber, Gerlinde Maria and Milkovi\'{c}-Peri\v{s}a, Marija and Haberler, Christine and Bettelheim, Dieter and Kasprian, Gregor and Juda\v{s}, Milo\v{s} and Prayer, Daniela and Jovanov-Milo\v{s}evi\'{c}, Nata\v{s}a}, year = {2021}, pages = {67-73}, DOI = {10.1016/j.ejpn.2021.09.014}, keywords = {malformations of cortical development, subplate, extracellular matrix, postmortem MRI, brain tissue shrinkage}, journal = {European journal of paediatric neurology}, doi = {10.1016/j.ejpn.2021.09.014}, volume = {35}, issn = {1090-3798}, title = {3T MRI signal intensity profiles and thicknesses of transient zones in human fetal brain at mid-gestation}, keyword = {malformations of cortical development, subplate, extracellular matrix, postmortem MRI, brain tissue shrinkage} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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