Naslov
Is frontolateral laryngectomy still useful procedure in the treatment of laryngeal malignancy in the modern era?

Autori
Tudor Filip ; Maršić Matej ; Malvić Goran ; Hadžisejdić Ita ; Maržić Diana ; Braut Tamara ; Velepič Marko ; Marijić Blažen

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Libri Oncologici : Croatian Journal of Oncology, Vol. 50 No. Supplement 1, 2022. / Vrdoljak, Eduard ; Jazvić, Marijana - Zagreb : University Hospital for Tumors, Zagreb, Croatia, 2022, 122-123

Skup
15. hrvatski onkološki kongres (HOK 2022)

Mjesto i datum
Opatija, Hrvatska, 31.03.2022. - 03.04.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
laryngeal carcinoma, partial laryngectomy, survival, recurrence

Sažetak
Background: Over the last few decades there have been some groundbreaking changes in the treatment of the head and neck tumors, particularly laryngeal tumors. However, there is still room for improvement because mortality rate is still relatively high. According to NCCN guidelines (version 3.2021), the treatment modalities of early stage glottic malignancy are radiotherapy, laryngeal laser resection or partial laryngectomy. Our experiences with patients who underwent frontolateral laryngectomy are presented. Methods: Patients with an early stage glottic malignancy treated with frontolateral laryngectomy at a tertiary care center were included in this retrospective study. Patient’s demographics, tumor stage, histopathological examination and oncological outcome were evaluated. Results: 45 patients were treated with aforementioned surgery due to T1 (60%) or T2 (40%) laryngeal squamous cell cancer without nodal involvement. 3 female (6, 7%) and 42 male (93, 3%) patients were included in the study. Mean age was 62, 7 ± 8, 1 years. Only 2 patients experienced local and one regional recurrence. Both patients who developed local recurrences had anterior commissure involvement. 5-year disease specific survival was 100%. 5-year overall survival was 93, 3%. During the follow-up (mean 92 months) ten patients died. Secondary primary tumors or other causes unrelated to primary cancer were the causes of death. Complications, granuloma and synechia, were noticed in 7 and 1 patients, respectively. Conclusion: Laryngeal cancer has a very good prognosis when its caught at early stage. When results were compared to the results of studies where the treatment modality was RT, laser surgery or transoral robotic surgery, a similar success rate was observed. Certainly, new modalities have some advantages, but in certain cases of patients, frontolateral laryngectomy is a viable option.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA