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Pregled bibliografske jedinice broj: 1211988

Synthesis, photophysical properties, anti-Kasha photochemical reactivity and biological activity of vinyl- and alkynyl-BODIPY derivatives


Zlatić, Katarina; Bogomolec, Marko; Cindrić, Matej; Uzelac, Lidija; Basarić, Nikola
Synthesis, photophysical properties, anti-Kasha photochemical reactivity and biological activity of vinyl- and alkynyl-BODIPY derivatives // Tetrahedron, 124 (2022), 1-9 doi:10.1016/j.tet.2022.132995 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1211988 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Synthesis, photophysical properties, anti-Kasha photochemical reactivity and biological activity of vinyl- and alkynyl-BODIPY derivatives
(Synthesis, photophysical properties, anti-Kasha photochemical reactivity and biological activity of vinyl- and alkynyl-BODIPY derivatives)

Autori
Zlatić, Katarina ; Bogomolec, Marko ; Cindrić, Matej ; Uzelac, Lidija ; Basarić, Nikola

Izvornik
Tetrahedron (0040-4020) 124 (2022); 1-9

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Anti-Kasha photochemistry ; Antiproliferative activity ; BODIPY ; Quinone methides

Sažetak
New photoactivable BODIPY fluorescent dyes, which are quinone methide (QM) precursors, were synthesized. The series of BODIPY dyes has a photoreactive group linked to the BODIPY core by vinyl or ethynyl spacers. Molecules have bathochromic shifted absorption and emission maxima and higher fluorescence quantum yields compared to the previously reported BODIPY QM precursors. They show anti-Kasha photochemical reactivity and undergo photomethanolysis reaction upon photoexcitation at λ < 350 nm. Although UV light is needed for the photochemical generation of QMs and attachment to potential bio-targets, bathochromic shifted absorption and emission has advances in sensing and fluorescence labeling. Antiproliferative investigation was conducted for the vinyl derivative against three human cancer lines with the cells kept in dark or irradiated. Upon excitation with visible light antiproliferative activity was enhanced with IC50 values in low micromolar concentration.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekti:
--IP-2019-04-8008 - Fotokemija: Reakcijski mehanizmi i primjene u organskoj sintezi i biologiji (PhotoApp) (Basarić, Nikola) ( CroRIS)

Ustanove:
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Lidija Uzelac (autor)

Avatar Url Matej Cindrić (autor)

Avatar Url Katarina Zlatić (autor)

Avatar Url Nikola Basarić (autor)

Poveznice na cjeloviti tekst rada:

doi www.sciencedirect.com

Citiraj ovu publikaciju:

Zlatić, Katarina; Bogomolec, Marko; Cindrić, Matej; Uzelac, Lidija; Basarić, Nikola
Synthesis, photophysical properties, anti-Kasha photochemical reactivity and biological activity of vinyl- and alkynyl-BODIPY derivatives // Tetrahedron, 124 (2022), 1-9 doi:10.1016/j.tet.2022.132995 (međunarodna recenzija, članak, znanstveni)
Zlatić, K., Bogomolec, M., Cindrić, M., Uzelac, L. & Basarić, N. (2022) Synthesis, photophysical properties, anti-Kasha photochemical reactivity and biological activity of vinyl- and alkynyl-BODIPY derivatives. Tetrahedron, 124, 1-9 doi:10.1016/j.tet.2022.132995.
@article{article, author = {Zlati\'{c}, Katarina and Bogomolec, Marko and Cindri\'{c}, Matej and Uzelac, Lidija and Basari\'{c}, Nikola}, year = {2022}, pages = {1-9}, DOI = {10.1016/j.tet.2022.132995}, keywords = {Anti-Kasha photochemistry, Antiproliferative activity, BODIPY, Quinone methides}, journal = {Tetrahedron}, doi = {10.1016/j.tet.2022.132995}, volume = {124}, issn = {0040-4020}, title = {Synthesis, photophysical properties, anti-Kasha photochemical reactivity and biological activity of vinyl- and alkynyl-BODIPY derivatives}, keyword = {Anti-Kasha photochemistry, Antiproliferative activity, BODIPY, Quinone methides} }
@article{article, author = {Zlati\'{c}, Katarina and Bogomolec, Marko and Cindri\'{c}, Matej and Uzelac, Lidija and Basari\'{c}, Nikola}, year = {2022}, pages = {1-9}, DOI = {10.1016/j.tet.2022.132995}, keywords = {Anti-Kasha photochemistry, Antiproliferative activity, BODIPY, Quinone methides}, journal = {Tetrahedron}, doi = {10.1016/j.tet.2022.132995}, volume = {124}, issn = {0040-4020}, title = {Synthesis, photophysical properties, anti-Kasha photochemical reactivity and biological activity of vinyl- and alkynyl-BODIPY derivatives}, keyword = {Anti-Kasha photochemistry, Antiproliferative activity, BODIPY, Quinone methides} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


Citati:





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