New derivatives of tylosin : Chemical and electrochemical oxidation products of desmycosin

Mandić, Zoran; Naranđa, Amalija; Novak, Predrag; Brajša, Karmen; Đerek, Marko; Iveković, Damir

doi:10.7164/antibiotics.55.807

Pregled bibliografske jedinice broj: 120816

New derivatives of tylosin : Chemical and electrochemical oxidation products of desmycosin

Mandić, Zoran; Naranđa, Amalija; Novak, Predrag; Brajša, Karmen; Đerek, Marko; Iveković, Damir

New derivatives of tylosin : Chemical and electrochemical oxidation products of desmycosin // Journal of antibiotics, 55 (2002), 9; 807-813 doi:10.7164/antibiotics.55.807 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 120816 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
New derivatives of tylosin : Chemical and electrochemical oxidation products of desmycosin

Autori
Mandić, Zoran ; Naranđa, Amalija ; Novak, Predrag ; Brajša, Karmen ; Đerek, Marko ; Iveković, Damir

Izvornik
Journal of antibiotics (0021-8820) 55 (2002), 9; 807-813

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
oxirane ring

Sažetak
Chemical and electrochemical oxidation of dienonic moiety of desmycosin were carried out. Successive chemical oxidation of desmycosin with m-chloroperbenzoic acid afforded a family of 12, 13-dihydro-12, 13-dihydroxy derivatives. Indirect electrochemical oxidation via hypobromite as an intermediate gave rise to the new bicyclo derivative of desmycosin, 13- hydroxy-3-dehydroxy-3, 12-oxa-desmycosin.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Kemijsko inženjerstvo, Temeljne medicinske znanosti, Farmacija

POVEZANOST RADA

Projekti:
0098109

Ustanove:
Institut "Ruđer Bošković", Zagreb

Profili:

Damir Iveković (autor)