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Pregled bibliografske jedinice broj: 1207035

Dynamic Contrast Enhanced Study in Multiparametric Examination of the Prostate—Can We Make Better Use of It?


Guljaš, Silva; Benšić, Mirta; Krivdić Dupan, Zdravka; Pavlović, Oliver; Krajina, Vinko; Pavoković, Deni; Šmit Takač, Petra; Hranić, Matija; Salha, Tamer
Dynamic Contrast Enhanced Study in Multiparametric Examination of the Prostate—Can We Make Better Use of It? // Tomography, 8 (2022), 3; 1509-1521 doi:10.3390/tomography8030124 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1207035 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Dynamic Contrast Enhanced Study in Multiparametric Examination of the Prostate—Can We Make Better Use of It?

Autori
Guljaš, Silva ; Benšić, Mirta ; Krivdić Dupan, Zdravka ; Pavlović, Oliver ; Krajina, Vinko ; Pavoković, Deni ; Šmit Takač, Petra ; Hranić, Matija ; Salha, Tamer

Izvornik
Tomography (2379-1381) 8 (2022), 3; 1509-1521

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
magnetic resonance imaging ; muscle, perfusion ; permeability ; prostate cancer
(magnetic resonance imaging ; muscle ; perfusion ; permeability ; prostate cancer)

Sažetak
We sought to investigate whether quantitative parameters from a dynamic contrast-enhanced study can be used to differentiate cancer from normal tissue and to determine a cut-off value of specific parameters that can predict malignancy more accurately, compared to the obturator internus muscle as a reference tissue. This retrospective study included 56 patients with biopsy proven prostate cancer (PCa) after multiparametric magnetic resonance imaging (mpMRI), with a total of 70 lesions ; 39 were located in the peripheral zone, and 31 in the transition zone. The quantitative parameters for all patients were calculated in the detected lesion, morphologically normal prostate tissue and the obturator internus muscle. Increase in the Ktrans value was determined in lesion-to-muscle ratio by 3.974368, which is a cut-off value to differentiate between prostate cancer and normal prostate tissue, with specificity of 72.86% and sensitivity of 91.43%. We introduced a model to detect prostate cancer that combines Ktrans lesion-to-muscle ratio value and iAUC lesion-to- muscle ratio value, which is of higher accuracy compared to individual variables. Based on this model, we identified the optimal cut-off value with 100% sensitivity and 64.28% specificity. The use of quantitative DCE pharmacokinetic parameters compared to the obturator internus muscle as reference tissue leads to higher diagnostic accuracy for prostate cancer detection.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Klinički bolnički centar Osijek,
Medicinski fakultet, Osijek,
Sveučilište u Osijeku, Odjel za matematiku,
Fakultet za dentalnu medicinu i zdravstvo, Osijek

Poveznice na cjeloviti tekst rada:

Pristup cjelovitom tekstu rada doi www.mdpi.com

Citiraj ovu publikaciju:

Guljaš, Silva; Benšić, Mirta; Krivdić Dupan, Zdravka; Pavlović, Oliver; Krajina, Vinko; Pavoković, Deni; Šmit Takač, Petra; Hranić, Matija; Salha, Tamer
Dynamic Contrast Enhanced Study in Multiparametric Examination of the Prostate—Can We Make Better Use of It? // Tomography, 8 (2022), 3; 1509-1521 doi:10.3390/tomography8030124 (međunarodna recenzija, članak, znanstveni)
Guljaš, S., Benšić, M., Krivdić Dupan, Z., Pavlović, O., Krajina, V., Pavoković, D., Šmit Takač, P., Hranić, M. & Salha, T. (2022) Dynamic Contrast Enhanced Study in Multiparametric Examination of the Prostate—Can We Make Better Use of It?. Tomography, 8 (3), 1509-1521 doi:10.3390/tomography8030124.
@article{article, author = {Gulja\v{s}, Silva and Ben\v{s}i\'{c}, Mirta and Krivdi\'{c} Dupan, Zdravka and Pavlovi\'{c}, Oliver and Krajina, Vinko and Pavokovi\'{c}, Deni and \v{S}mit Taka\v{c}, Petra and Hrani\'{c}, Matija and Salha, Tamer}, year = {2022}, pages = {1509-1521}, DOI = {10.3390/tomography8030124}, keywords = {magnetic resonance imaging, muscle, perfusion, permeability, prostate cancer}, journal = {Tomography}, doi = {10.3390/tomography8030124}, volume = {8}, number = {3}, issn = {2379-1381}, title = {Dynamic Contrast Enhanced Study in Multiparametric Examination of the Prostate—Can We Make Better Use of It?}, keyword = {magnetic resonance imaging, muscle, perfusion, permeability, prostate cancer} }
@article{article, author = {Gulja\v{s}, Silva and Ben\v{s}i\'{c}, Mirta and Krivdi\'{c} Dupan, Zdravka and Pavlovi\'{c}, Oliver and Krajina, Vinko and Pavokovi\'{c}, Deni and \v{S}mit Taka\v{c}, Petra and Hrani\'{c}, Matija and Salha, Tamer}, year = {2022}, pages = {1509-1521}, DOI = {10.3390/tomography8030124}, keywords = {magnetic resonance imaging, muscle, perfusion, permeability, prostate cancer}, journal = {Tomography}, doi = {10.3390/tomography8030124}, volume = {8}, number = {3}, issn = {2379-1381}, title = {Dynamic Contrast Enhanced Study in Multiparametric Examination of the Prostate—Can We Make Better Use of It?}, keyword = {magnetic resonance imaging, muscle, perfusion, permeability, prostate cancer} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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