Naslov
Changes in specific biomarkers indicate cardioprotective and anti-inflammatory effects of recreational SCUBA diving
(Changes in specific biomarkers indicate cardioprotective and anti-inflammatory effects of recreational SCUBA diving)

Autori
Žarak, Marko ; Cvetko, Ana ; Abramović, Irena ; Šupraha Goreta, Sandra ; Perović, Antonija ; Njire Bratičević, Marina ; Kifer, Domagoj ; Sinčić, Nino ; Gornik, Olga ; Dumić, Jerka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
FEBS Open Bio, 12 (2022), Suppl 1 / - , 2022, 201-201

Skup
The Biochemistry Global Summit

Mjesto i datum
Lisabon, Portugal, 06.07.2022. - 14.07.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
cardioprotective ; anti-inflammatory ; SCUBA diving ; N-glycans

Sažetak
Recreational SCUBA (rSCUBA) diving is a specific type of underwater activity preformed in extreme environmental conditions. However, information on molecular events underlying (patho)physiological events that follow exposure to such conditions is still largely unexplored. To contribute to better understanding cardiac and immune system adaptation mechanisms triggered by repeated rSCUBA diving we measured copeptin, IgA, IgG, and IgM, complement components C3 and C4, and differential blood count parameters, including neutrophil­to­lymphocyte ratio (NLR), N­glycosylation of IgG and total plasma proteins (TPP), as well as cell­free DNA in blood samples of fourteen recreational male divers who performed five dives, one per week, on the depth 20­30 m for 30 min, after non­dive period of 5 months. Changes in measured parameters suggested that first dive triggered stress response that was abolished with repetition of diving since its beneficial effects on cardiac system (copeptin level) and immune status (NLR, immunoglobulins level, as well as IgG and TPP N­glycosylation pattern towards anti­inflammatory status) were observed after the following dives. In conclusion, rSCUBA diving practiced on a regular basis induce cardiac adaptive response and promotes anti­ inflammatory status of the organism thus conferring cardioprotection as well as multiple health benefits.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA