Naslov
Simultaneous influence of titanate nanomaterials and chitosan on precipitation of calcium phosphate

Autori
Erceg, Ina ; Milisav, Ana-Marija ; Strasser, Vida ; Dutour Sikirić, Maja

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
4th Croatian Microscopy Congress with nternational Participation: Book of Abstracts / Macan, Jelena ; Kovačević, Goran - Zagreb : Hrvatsko mikroskopijsko društvo ; Institut Ruđer Bošković, 2022, 53-53

ISBN
978-953-7941-41-3

Skup
4th Croatian Microscopy Congress (CMC 2022)

Mjesto i datum
Poreč, Hrvatska, 18.05.2022. - 20.05.2022

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Domaća recenzija

Ključne riječi
calcium phosphates ; chitosan ; titanate nanomaterials

Sažetak
The increased frequency of hard tissue diseases, which commonly can be treated only by implantation, is motivating research of materials’ new innovative designs as well as green and low-cost routes of fabrication. In this sense, composites of calcium phosphates (CaPs) with inorganic nanomaterials or organic macromolecules attract special attention. In addition to replacing missing tissue or enabling its regeneration, they can have improved mechanical properties and/or act as a local drug delivery system [1]. In order for these materials to be functional and to rationalize their design, the interactions between CaPs and additives should be understood. This is very often not the case, and success stories are often a result of a more empirical rather than a systematic approach. To fill this void, in this study the simultaneous influence of titanate nanomaterials and chitosan on the precipitation of CaPs was investigated. Titanate nanomaterials are proposed as additives which can improve CaP mechanical properties, while chitosan is biocompatible [2]. To the best of our knowledge, the studies on the precipitation of CaP in the simultaneous presence of two additives are rare. Four different classes of TiNMs, namely nanoparticles (TiNP), nanowires (TiNW), nanotubes (TiNT), and nanoplates (TiNPl), were synthesized by hydrothermal methods, and their composites with CaPs were synthesized by precipitation from solutions. In order to obtain multifunctional composites, chitosan was added simultaneously with TiNM in the precipitation systems. The progress of precipitation was followed by potentiometric measurements. The precipitated composites were characterized by Fourier transform infrared spectroscopy (FTIR), powder X-ray diffraction (PXRD) and scanning electron microscopy (SEM). The obtained results show that precipitation of CaP in the presence of TiNMs and chitosan can be used as a fast and versatile method for the preparation of CaP/TiNM composites. Neither class of additives had an effect on the structure or composition of the formed composites, either added alone or simultaneously. However, an effect on the morphology of the CaPs was observed. The obtained results will provide a deeper insight into the precipitation processes on nanosurfaces, which will enable a rational approach in synthesis of novel composites for hard tissue regeneration and various other applications.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Interdisciplinarne prirodne znanosti

POVEZANOST RADA