Naslov
An Eco-Friendly Preparations Of Isonicotinamide Quaternary Salts In Deep Eutectic Solvents

Autori
Gašo-Sokač, Dajana ; Bušić, Valentina ; Molnar, Maja

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
27th Croatian meeting of chemists and chemical engineers : 27. Hrvatski skup kemičara i kemijskih inženjera 5–8 October 2021, Veli Lošinj, Croatia / Marković, D ; Meštrović, E ; Namjesnik, D ; Tomašić, V - Zagreb : Hrvatsko kemijsko društvo, 2021, 99-99

Skup
27. hrvatski skup kemičara i kemijskih inženjera (27HSKIKI) ; 5. simpozij Vladimir Prelog

Mjesto i datum
Veli Lošinj, Hrvatska, 05.10.2021. - 08.10.2021

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
kvaterne soli ; eutektička otapala ; mikrovalna sinteza ; ultrazvučna sinteza
(quaternary salts ; deep eutectic solvents ; microwave synthesis ; ultrasopund synthesis)

Sažetak
Deep eutectic solvents (DES) are liquids composed of two or three safe, inexpensive components, often interconnected by noncovalent hydrogen bonds which produce eutectic mixture whose melting point is lower than that of each component. No data in literature have been found on the quaternization reaction in DES. The use of DES have several advantages: they are environmentally benign and biodegradable, easy for purification and simple for preparation. An environmentally sustainable method for preparing quaternary salts of izonicotinamide and substituted 2- bromoacetophenones was demonstrated here using choline chloride-based DES. The quaternization reaction was carried out by three synthetic approaches: conventional method, microwave and ultrasonic irradiation. Results showed that the high reaction yields, the easy environment- friendly solvents and short reaction times are in agreement with principles of green chemistry, making microwave method as a new approach for preparation of quaternary salts in DES.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

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