Naslov
Hernia Sac Presence Portends Better Survivability of Isolated Congenital Diaphragmatic Hernia with “Liver-Up”

Autori
Grizelj, Ruža ; Bojanić, Katarina ; Vuković, Jurica ; Novak, Milivoj ; Weingarten, Toby ; Schroeder, Darrell ; Sprung, Juraj

Izvornik
American Journal of Perinatology (0735-1631) 34 (2017), 05; 515-519

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
congenital diaphragmatic hernia - hernia sac - liver-up - mortality - outcome - risk assessment - survival

Sažetak
Abstract Objective: The objective of this study was to investigate the prognostic value of a hernia sac in isolated congenital diaphragmatic hernia (CDH) with intrathoracic liver herniation (“liver-up”). Study Design: A retrospective study from the single tertiary center. Isolated “liver-up” CDH neonates referred to our institution between 2000 and 2015 were reviewed for the presence or absence of a hernia sac. Association between the presence of a hernia sac and survival was assessed. Results: Over the study period, there were 29 isolated CDH patients with “liver-up” who were treated, 7 (24%) had a sac, and 22 (76%) did not. Demographics were similar between groups. However, disease acuity, assessed from lower Apgar scores (p = 0.044), lower probability of survival (p = 0.037), and lower admission oxygenation (p = 0.027), was higher in neonates without a sac. Hospital survival was significantly higher for those with sac compared with those without (7/7, 100 vs. 7/22, 32%, p = 0.002). Conclusion: The presence of a hernia sac may be associated with better survival for isolated “liver-up” CDH. As the presence of sac can be prenatally detected, it may be a useful marker to aid perinatal decision making.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA