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Pregled bibliografske jedinice broj: 1196009

Human adenovirus type 26 basic biology and its usage as vaccine vector

Majhen, Dragomira
Human adenovirus type 26 basic biology and its usage as vaccine vector // Reviews in medical virology, 32 (2022), 6; e2338, 11 doi:10.1002/rmv.2338 (međunarodna recenzija, pregledni rad, znanstveni)

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Naslov
Human adenovirus type 26 basic biology and its usage as vaccine vector

Autori
Majhen, Dragomira

Izvornik
Reviews in medical virology (1052-9276) 32 (2022), 6; E2338, 11

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
adenovirus ; adenovirus type 26 ; vaccination ; vaccine vector ; virus vector

Sažetak
Due to their nature, adenoviruses have been recognised as promising candidates for vaccine vector development. Since they mimic natural infection, recombinant adenovirus vectors have been proven as ideal shuttles to deliver foreign transgenes aiming at inducing both humoral and cellular immune response. In addition, a potent adjuvant effect can be exerted due to the adenovirus inherent stimulation of various elements of innate and adaptive immunity. Due to its low seroprevalence in humans as well as induction of favourable immune response to inserted transgene, human adenovirus type 26 (HAdV-D26) has been recognised as a promising platform for vaccine vector development and is studied in number of completed or ongoing clinical studies. Very recently HAdV-D26 based Ebola and Covid-19 vaccines were approved for medical use. In this review, current state of the art regarding HAdV-D26 basic biology and its usage as vaccine vector will be discussed.

Izvorni jezik
Engleski

Znanstvena područja
Biologija



POVEZANOST RADA

Projekti:
HRZZ-IP-2019-04-6048 - Endocitoza adenovirusa i urođeni imunosni odgovor (AdenoIN) (Majhen, Dragomira, HRZZ - 2019-04) ( CroRIS)

Ustanove:
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Dragomira Majhen (autor)

Poveznice na cjeloviti tekst rada:

doi onlinelibrary.wiley.com

Citiraj ovu publikaciju:

Majhen, Dragomira
Human adenovirus type 26 basic biology and its usage as vaccine vector // Reviews in medical virology, 32 (2022), 6; e2338, 11 doi:10.1002/rmv.2338 (međunarodna recenzija, pregledni rad, znanstveni)
Majhen, D. (2022) Human adenovirus type 26 basic biology and its usage as vaccine vector. Reviews in medical virology, 32 (6), e2338, 11 doi:10.1002/rmv.2338.
@article{article, author = {Majhen, Dragomira}, year = {2022}, pages = {11}, DOI = {10.1002/rmv.2338}, chapter = {e2338}, keywords = {adenovirus, adenovirus type 26, vaccination, vaccine vector, virus vector}, journal = {Reviews in medical virology}, doi = {10.1002/rmv.2338}, volume = {32}, number = {6}, issn = {1052-9276}, title = {Human adenovirus type 26 basic biology and its usage as vaccine vector}, keyword = {adenovirus, adenovirus type 26, vaccination, vaccine vector, virus vector}, chapternumber = {e2338} }
@article{article, author = {Majhen, Dragomira}, year = {2022}, pages = {11}, DOI = {10.1002/rmv.2338}, chapter = {e2338}, keywords = {adenovirus, adenovirus type 26, vaccination, vaccine vector, virus vector}, journal = {Reviews in medical virology}, doi = {10.1002/rmv.2338}, volume = {32}, number = {6}, issn = {1052-9276}, title = {Human adenovirus type 26 basic biology and its usage as vaccine vector}, keyword = {adenovirus, adenovirus type 26, vaccination, vaccine vector, virus vector}, chapternumber = {e2338} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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