Pregled bibliografske jedinice broj: 1194618
Inclusion complexes of ferrocene uracil derivatives with cyclodextrins: solubilization and binding ability
Inclusion complexes of ferrocene uracil derivatives with cyclodextrins: solubilization and binding ability // Supramolecular chemistry 2021 : Book of abstracts / Frkanec, Leo ; Tomišić, Vladislav (ur.).
Zagreb: Institut Ruđer Bošković, 2021. str. 12-12 (predavanje, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 1194618 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Inclusion complexes of ferrocene uracil
derivatives with cyclodextrins: solubilization and
binding ability
Autori
Gazdek, Nika ; Drobac, Dunja ; Usenik, Andrea ; Halasz, Ivan ; Maračić, Silvija ; Lapić, Jasmina ; Raić-Malić, Silvana ; Djaković, Senka ; Tomišić, Vladislav ; Frkanec, Ruža ; Frkanec, Leo ;
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Supramolecular chemistry 2021 : Book of abstracts
/ Frkanec, Leo ; Tomišić, Vladislav - Zagreb : Institut Ruđer Bošković, 2021, 12-12
ISBN
978-953-7941-39-0
Skup
4. simpozij supramolekulske kemije
Mjesto i datum
Zagreb, Hrvatska, 10.12.2021
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
complex ; ferrocene uracil ; cyclodextrin
Sažetak
Recent research shows that ferrocene uracil derivatives have biological activity. However, their high lipophilicity limits the application. It is known that cyclodextrins show abillity to improve drug water solubility by binding the hidrophobic moiety of the molecule inside of its cavity, such as ferrocene.2 Ferrocene shows different binding orientations as well as binding constants for alpha, beta and gama cyclodextrine in water.3 Environment of ferrocene can influence their binding to cyclodextrines. Therefore, we researched various ferocene uracyl derivatives with different R’, R groups and studied their binding ability with α-cyclodextrin, β- cyclodextrin, γ-cyclodextrin and modified (2- hydroxypropyl)-β-cyclodextrin in water. Characterisation was preformed using UV-Vis spectroscopy. Titrations were used to calculate binding constants that show range between.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Projekti:
HRZZ-IP-2018-01-6910 - Sinteza supramolekulskih samo-udruženih nanostruktura za izgradnju naprednih funkcionalnih materijala (SUPeRNANO) (Frkanec, Leo, HRZZ - 2018-01) ( CroRIS)
Ustanove:
Prehrambeno-biotehnološki fakultet, Zagreb,
Institut "Ruđer Bošković", Zagreb,
Prirodoslovno-matematički fakultet, Zagreb,
Fakultet kemijskog inženjerstva i tehnologije, Zagreb,
Sveučilište u Zagrebu
Profili:
Leo Frkanec (autor)
Silvija Maračić (autor)
Andrea Usenik (autor)
Jasmina Lapić (autor)
Nika Gazdek Serdar (autor)
Vladislav Tomišić (autor)
Ivan Halasz (autor)
Silvana Raić-Malić (autor)
Ruža Frkanec (autor)
Senka Djaković (autor)