Naslov
Intracoronary thrombus formation on a guide wire: who is to blame?

Autori
Maric Besic, Kristina ; Baricevic, Zeljko ; Strozzi, Maja

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, prošireni sažetak, stručni

Skup
VII. nacionalni sastanak o kardiovaskularnim intervencijama s međunarodnim sudjelovanjem, VI. sastanak intervencijskih kardioloških medicinskih sestara i tehničara, Crointervent 2016

Mjesto i datum
Zagreb, Hrvatska, 10.03.2016. - 12.03.2016

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Domaća recenzija

Ključne riječi
percutaneous coronary intervention, intracoronary thrombus, guide wire

Sažetak
Pharmacotherapy during PCI is used to mitigate the sequel of iatrogenic plaque rupture and to reduce the risk of thrombus formation on intravascular PCI equipment. Iatrogenic damage to the endothelium leads to increased expression of tissue factor and activation of the coagulation cascade, ultimately leading to thrombus formation1 . Anticoagulation with UFH alone does not seem to be sufficient for protection from ischemic sequel, such as periprocedural myocardial infarction. One cause of these events is embolization of platelet aggregates that form as a result of platelet activationinduced by UFH2 and the prevention of thrombus formation strongly depends on platelet inhibition by dual antiplatelet therapy. In cases with high-risk plaque features, a care has to be taken to recognize iatrogenic damage in a timely manner. Usefulness of clopidogrel resistance testing before complex PCI has yet to be shown.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA