Naslov
Perinatal outcome of pregnancies in women aged 40 and over

Autori
Miletić, Tomislav ; Aberle, Neda ; Mikulandra, Frane ; Karelović, Deni ; Zakanj, Zora ; Banović, Ivo ; Tadin, Ivica ; Periša, Mila ; Ognjenović, Mladen ; Tadić, Tade

Izvornik
Collegium antropologicum (0350-6134) 26 (2002), 1; 251-258

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
pregnancy at 40 and over; perinatal mortality; delivery; newborn

Sažetak
Perinatal outcome of pregnancies at forty and over was analyzed from diagnosing the pregnancy to seven days following delivery. Retrospectively, pre-gestational health and reproduction status were dealt with, as well as the course of pregnancy, deliveries, and newborn children. The Control Group was composed of pregnant women aged 20 to 29, who were identical to Study Group in terms of parity. Out of 2.099 diagnosed wanted pregnancies at forty and over, 415 (19.8%) had a miscarriage, in 33 (1.6%) an artificial abortion was performed after determining the fetus karyotype and 1, 651 (78.2%) of pregnant women delivered. In 66.2% of pregnancies the fetus karyotype was determined and in 33 (2.5%) fetuses chromosomal abnormalities were found.Incidence of deliveries at 40 and over is 1.38%, which is a 35.6-percent increase in the last ten years. Nullipara and pluripara had an increase, and multipara had a decrease. Pre-gestational health and reproduction status in Study Group is lower than in Control Group. Complications during pregnancy: threatend abortion, EPH gestosis, placenta praevia, gestational diabetes, late fetal death are more frequent than in Control Group (p<0.05). In intrapartal terms, more frequent were induction of delivery, meconium-stainedamniotic fluid, fetal distress, operative vaginal deliveries, and Caesarean section (p<0.05). In neonatal outcome there are more premature infant, there are more VLBW, LBW, SGA, newborn with low Apgar index values, and the total perinatal death is greater than in the Control Group (p<0.05). In perinatal terms, (from the diagnosis to the seventh day following delivery) 1, 617 children survived (77.0%), meaning that perinatal loss was 482 (23.0%). Conclusions. Pregnancy at 40 and over is a high-risk pregnancy.There is a high risk of pre-gestational and gestational complications. Perinatal loss is high. Those pregnancies are not desirable from the medical point of viev.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA