Prevalence and risk factors for lymphocytic choriomeningitis virus infection in continental croatian regions

Vilibić-Čavlek, Tatjana; Oreški, Tena; Korva, Miša; Kolarić, Branko; Stevanović, Vladimir; Židovec-Lepej, Snježana; Tabain, Irena; Jeličić, Pavle; Miklaušić-Pavić, Božana; Savić, Vladimir; Barbić, Ljubo; Avšič-Županc, Tatjana

doi:10.3390/tropicalmed6020067

Pregled bibliografske jedinice broj: 1181224

Prevalence and risk factors for lymphocytic choriomeningitis virus infection in continental croatian regions

Vilibić-Čavlek, Tatjana; Oreški, Tena; Korva, Miša; Kolarić, Branko; Stevanović, Vladimir; Židovec-Lepej, Snježana; Tabain, Irena; Jeličić, Pavle; Miklaušić-Pavić, Božana; Savić, Vladimir et al.

Prevalence and risk factors for lymphocytic choriomeningitis virus infection in continental croatian regions // Tropical medicine and infectious disease, 6 (2021), 2; 67, 10 doi:10.3390/tropicalmed6020067 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 1181224 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Prevalence and risk factors for lymphocytic choriomeningitis virus infection in continental croatian regions

Autori
Vilibić-Čavlek, Tatjana ; Oreški, Tena ; Korva, Miša ; Kolarić, Branko ; Stevanović, Vladimir ; Židovec-Lepej, Snježana ; Tabain, Irena ; Jeličić, Pavle ; Miklaušić-Pavić, Božana ; Savić, Vladimir ; Barbić, Ljubo ; Avšič-Županc, Tatjana

Izvornik
Tropical medicine and infectious disease (2414-6366) 6 (2021), 2; 67, 10

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
lymphocytic choriomeningitis virus ; seroprevalence ; general population ; professionally exposed ; pregnant women ; Croatia

Sažetak
Lymphocytic choriomeningitis virus (LCMV) is a neglected human pathogen associated with aseptic meningitis, severe systemic infections in immunocompromised persons, and congenital anomalies. Data on the prevalence of LCMV infections are scarce. We analyzed the seroprevalence of LCMV in continental Croatian regions. A total of 338 serum samples of professionally exposed (forestry workers, hunters, agriculture workers in contact with rodents) and non-exposed populations (general population, pregnant women) were tested for the presence of LCMV antibodies using indirect immunofluorescence assay. No participants reported recent febrile disease. LCMV IgG antibodies were detected in 23/6.8% of participants: 9.8% exposed persons and 5.1% non-exposed persons (6.1% in the general population and 3.9% in pregnant women). No participants were LCMV IgM positive. Although higher seropositivity was found in males compared to females (8.9% vs. 4.7%), inhabitants of suburban/rural areas compared to inhabitants of urban areas (9.2% vs. 4.6%), and persons who used well as a source of water compared to those who used tap (11.4% vs. 5.6%), these differences did not reach statistical significance. Results of logistic regression showed that the presence of rodents in the house/yard and cleaning rodent nests were associated with an elevated risk for LCMV infection (OR = 2.962, 95% CI = 1.019–8.607).

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA

Ustanove:
Hrvatski zavod za javno zdravstvo,
Hrvatski veterinarski institut, Zagreb,
Veterinarski fakultet, Zagreb,
Medicinski fakultet, Rijeka,
Medicinski fakultet, Zagreb,
Nastavni zavod za javno zdravstvo "Dr. Andrija Štampar",
Klinika za infektivne bolesti "Dr Fran Mihaljević"

Profili:

Božana Miklaušić Pavić (autor)