Naslov
Rapid overlapping of Single Molecule High-Fidelity Sequencing Data

Autori
Pratljačić, Suzana

Vrsta, podvrsta i kategorija rada
Ocjenski radovi, diplomski rad, diplomski

Mjesto
Zagreb

Datum
20.09

Godina
2021

Stranica
40

Mentor
Šikić, Mile

Ključne riječi
HiFi PacBio reads ; DNA sequencing ; suffix array

Sažetak
In 2019, Pacific Bioscience introduced highly accurate long-read sequencing (HiFi sequencing), a paradigm that combines concepts from traditional short and long error-prone reads technologies. Long lengths and high base-level resolution characterize the HiFi fragments. These characteristics can be utilized to design algorithms that are less sensitive to errors. In this article, we present the novel algorithm for HiFi reads mapping. The algorithm is based on suffix arrays and a standard seed-chain-align procedure. We will analyze the performance and accuracy of the developed tool and compare it to state-of-the-art algorithms.

Izvorni jezik
Engleski

Znanstvena područja
Računarstvo

POVEZANOST RADA