Pregled bibliografske jedinice broj: 1177688
The antimicrobial activities of oleuropein and hydroxytyrosol
The antimicrobial activities of oleuropein and hydroxytyrosol // Promising antimicrobials from natural products / Rai, Mahendra ; Kosalec, Ivan (ur.).
Cham: Springer, 2022. str. 75-89 doi:10.1007/978-3-030-83504-0_5
CROSBI ID: 1177688 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
The antimicrobial activities of oleuropein and
hydroxytyrosol
Autori
Zorić, Nataša ; Kosalec, Ivan
Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, znanstveni
Knjiga
Promising antimicrobials from natural products
Urednik/ci
Rai, Mahendra ; Kosalec, Ivan
Izdavač
Springer
Grad
Cham
Godina
2022
Raspon stranica
75-89
ISBN
978-3-030-83503-3
Ključne riječi
antimicrobial activity ; oleuropein ; hydroxytyrosol ; Olea europea ; olive leaf extract
Sažetak
Several studies have reported that olive leaf extract and its constituents, particularly oleuropein and hydroxytyrosol, have health benefits including antioxidant and antimicrobial properties. Oleuropein and hydroxytyrosol have significant in vitro activity against fungi including opportunistic pathogen Candida albicans. Both compounds target virulence factors essential for the establishment of C. albicans infection. Both biomolecules express wide antibacterial activity in vitro. On the bacterial model Staphylococcus aureus, different targets have been detected. Oleuropein and hydroxytyrosol also interact with biofilm formation and could potentiate the activity of ampicillin. Considering the growing resistance to existing therapeutics has triggered the need for the development of new antimicrobial drugs, based on the presented results in this chapter, it seems that oleuropein and its derivative hydroxytyrosol could be considered as promising candidates for the treatment and/or prevention of candidiasis, and local infections caused by bacteria.
Izvorni jezik
Engleski
Znanstvena područja
Farmacija
