Naslov
Chal-lenges of blood compatibilitiy testing and blood transfusion in patients treated with anti- CD38 monoclonal antibody

Autori
Raos, Mirela ; Bojanić, Ines ; Bašić Kinda, Sandra ; Batinić, Josip ; Lukić, Marija ; Plenković, Fini ; Golubić Ćepulić, Branka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Skup
36th International ISBT Congress

Mjesto i datum
Barcelona, Španjolska, 12.12.2020. - 16.12.2020

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Podatak o recenziji nije dostupan

Ključne riječi
Chal-lenges, blood compatibilitiy testing , blood transfusion, anti-CD38 monoclonal antibody

Sažetak
Both procedures used in our laboratory, RBC treatment with 0.2 M dithiothreitol-treated RBCs and neutralization test using DaraEx reagent, have not been shown to be sufficiently reliable in resolving the interference with the routine blood compatibility testing caused by the anti-CD38 monoclonal antibody. Therefore, for blood transfusion of these patients it is necessary to provide antigenmatched RBC units. Good collaboration between the ward and the transfusion service, with protocols in place for blood compatibility testing and blood transfusion, remains a precondition for timely and safe blood transfusion for this group of patients.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

POVEZANOST RADA