Pregled bibliografske jedinice broj: 1165053
Is the extent of left atrial fibrosis associated with body mass index in patients undergoing pulmonary vein isolation for atrial fibrillation?
Is the extent of left atrial fibrosis associated with body mass index in patients undergoing pulmonary vein isolation for atrial fibrillation? // Kardiologia Polska, 79 (2021), 5; 531-538 doi:10.33963/kp.15910 (međunarodna recenzija, članak, ostalo)
CROSBI ID: 1165053 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Is the extent of left atrial fibrosis associated
with body mass index in patients undergoing
pulmonary vein isolation for atrial fibrillation?
Autori
Nossan, Janko Szavits ; Šesto, Igor ; Štambuk, Krešimir ; Šipić, Tomislav ; Bernat, Robert ; Gudelj, Ivan ; Rotkvić, Luka ; Žulj, Marinko ; Mirat, Jure
Izvornik
Kardiologia Polska (0022-9032) 79
(2021), 5;
531-538
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo
Ključne riječi
Atrial fibrillation ; Body mass index ; Fibrosis ; Pulmonary vein isolation ; Recurrence
Sažetak
Background: Left atrial (LA) fibrosis is associated with a higher rate of recurrence of atrial fibrillation (AF) after pulmonary vein isolation (PVI). Body mass index (BMI) is strongly associated with the prevalence of AF, but there is insufficient data about the association between BMI and LA fibrosis. Aims: The aim of the study was to examine the association between LA fibrosis and BMI in patients with AF undergoing PVI. Methods: In 114 patients an electro-anatomical voltage map was created using the CARTO 3 three- dimensional system before PVI. The total fibrosis area (voltage criteria ≤0.5 mV), percentage, and the number of fibrotic areas were calculated. A general linear model was used to determine the differences in BMI with confounders between groups of patients with differing extents of fibrosis and numbers of focuses. Results: Advanced fibrosis was found in 53 (47%) patients, in up to 9 areas with a median of 2 and an interquartile range (IQR) of 0-3. The median total fibrotic area was 27.3 cm2 with an IQR of 0.1-30.3 cm2. Patients were stratified by percentage of fibrotic area: <5%, 5%-20%, 20%-35%, and above 35% ; no significant difference in mean BMI was found between the groups (P = 0.57). When stratified by the number of fibrotic areas (0, 1, 2, and ≥3 fibrotic areas), no difference in BMI was noted between the groups (P = 0.67). Conclusions: Fibrosis of the LA, as the strongest predictor of AF recurrence after PVI, does not correlate with BMI in patients with AF where PVI is indicated.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Projekti:
HRZZ-UIP-2019-04-5692 - Glikozilacija u kardiovaskularnim bolestima (GLYCARD) (Gudelj, Ivan, HRZZ - 2019-04) ( CroRIS)
Ustanove:
GENOS d.o.o.
Profili:
Marinko Žulj
(autor)
Krešimir Štambuk
(autor)
Jure Mirat
(autor)
Tomislav Šipić
(autor)
Ivan Gudelj
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE