Naslov
Soluble type III TGF-beta receptor as a potential novel biomarker for breast cancer
(Soluble type III TGF-beta receptor as a potential novel biomarker for breast cancer.)

Autori
Grgurević, Lovorka ; Jurišić, Darko ; Erjavec, Igor ; Trkulja, Vladimir ; Vukičević, Slobodan ; Svaguša, Tomo ; Hadžibegović, Irzal ; Kovačević, Lucija ; Dumić Čule, Ivo ; Stanec, Zdenko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
Knjiga sažetaka 7. hrvatskog kongresa laboratorijske dijagnostike / - , 2017, 30-30

Skup
7. HRVATSKI KONGRES LABORATORIJSKE DIJAGNOSTIKE

Mjesto i datum
Poreč, Hrvatska, 27.09.2017. - 01.10.2017

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Recenziran

Ključne riječi
TGFbrIIII, betaglycan, breast cancer, biomarker

Sažetak
Type III transforming growth factor beta receptor (TGFbrIII) modulates TGFbeta superfamily signaling. Its tutor tissue expression is downregulated in human breast cancer. We assumed that its soluble form (sTGFbrIII) could be detectable in plasma with potential use in diagnostics/follow-up of breast cancer patients. For this purpose, we aimed to develop an indirect ELISA for its quantification and test its utility in a cohort of women with breast cancer. Our data suggest a high potential of plasma sTGFbrIII as a vowel diagnostic and prognostic biomarker in breast cancer.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA