Naslov
Thermodynamics of complexation of alkali and alkaline earth metal cations by a phenanthridine- based calix[4]arene glycoconjugate

Autori
Modrušan, Matija ; Tomaš, Renato ; Glazer, Lucija ; Cindro, Nikola ; Leko, Katarina ; Tomišić, Vladislav

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
27th Croatian Meeting of Chemists and Chemical Engineers and 5th Symposium Vladimir Prelog : Book of Abstracts / Marković, Dean ; Meštrović, Ernest ; Namjesnik, Danijel ; Tomašić, Vesna - Zagreb : Hrvatsko kemijsko društvo, 2021, 183-183

Skup
27. hrvatski skup kemičara i kemijskih inženjera (27HSKIKI)

Mjesto i datum
Veli Lošinj, Hrvatska, 05.10.2021. - 08.10.2021

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
Calix[4]arene ; amide ; glycoconjugate ; thermodynamics ; fluorescence

Sažetak
Calixarene tertiary amide derivatives are well known to have very high affinities towards alkali and alkaline earth metal cations, and can be glycosylated to produce potentially water-soluble compounds. Those additionally bearing fluorescent moieties can be considered as very sensitive fluorimetric ion sensors due to the prominent sensitivity of fluorescence spectroscopy. In the scope of this work the binding affinity of fluorescent, phenanthridine-based calix[4]arene glycoconjugate towards alkali and alkaline earth metal cations was investigated by means of spectrophotometry, fluorimetry, microcalorimetry, and 1H NMR spectroscopy. The thermodynamic parameters of the corresponding complexation reactions (i.e. stability constants of the complexes formed, standard reaction Gibbs energies, enthalpies, and entropies) were determined and discussed regarding the charge density and solvation of the cations as well as structural properties of the ligand.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

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