Naslov
Moderate-to-vigorous physical activity is associated with higher bone mineral density in children with inflammatory bowel disease

Autori
Trivić, Ivana ; Sila, Sara ; Tripalo Batoš, Ana ; Mišak, Zrinjka ; Kolaček, Sanja ; Hojsak, Iva

Izvornik
Journal of pediatric gastroenterology and nutrition (0277-2116) 74 (2021), 1; 54-59

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
inflammatory bowel disease ; children ; physical activity ; body composition ; bone mineral density

Sažetak
Objectives: Decreased mineral bone density (BMD) and reduced lean body mass (LBM) are common amongst children with inflammatory bowel disease (IBD). The aim of our cross-sectional, observational study was to evaluate the relationship between BMD, body composition and physical activity (PA) in children with IBD in remission. Methods: Total body less head (TLBH) dual energy X-ray absorptiometry (DXA) was used to measure BMD, fat mass (FM) and lean body mass (LBM). Triaxial accelerometer for five consecutive days was used to objectivize PA. Results: 40 pediatric IBD patients in clinical remission (24 boys ; age 15.3 ± 0.4 years ; Crohn's disease (CD) n = 20, ulcerative colitis (UC) n = 18, inflammatory bowel disease-unclassified (IBD- U) n = 2) were recruited. Mean BMD was 0.940 g/cm2 and mean BMD Z-score was -0.42 ± 0.14. CD patients had significantly lower BMD than UC counterparts (p < 0.001). Average time spent in PA was 247.24 ± 16.71 min/day with 45.73 ± 8.22 min/day spent in moderate-to-vigorous PA (MVPA). We observed a significant positive correlation between the time spent in MVPA and BMD Z-score (p = 0.003) and LBM Z-score (p = 0.026). Multivariate analysis confirmed that the positive correlation of MVPA and BMD Z-score. There was no significant correlation between daily protein intake and BMD. Cumulative glucocorticoid dose negatively correlated with LBM Z-score (p = 0.003), but not with BMD Z-score (p = 0.069). Conclusions: This study points to a strong positive relationship between MVPA, LBM and BMD. Longitudinal studies are required in order to elucidate the modifiable processes that determine body health and favorable body composition.

Izvorni jezik
Engleski

Znanstvena područja
Interdisciplinarne prirodne znanosti, Kliničke medicinske znanosti, Nutricionizam, Kineziologija, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

POVEZANOST RADA