Naslov
Kliničke smjernice za dijagnosticiranje, liječenje i praćenje bolesnika s rakom mokraćnog mjehura
(Clinical guidelines for diagnosing, treatment and monitoring patients with bladder cancer)

Autori
Gamulin Marija, Ružić Ira Pavlović, Grgić Mislav, Jazvić Marijana, Solarić Mladen, Zahirović Dag, Zorica Robert, Omrčen Tomislav, Petković Marija, Matić Mate, Fučkar Zeljko, Ruzić Boris, Pasini Josip, Situm Marijan, Dordević Gordana, Miletić Damir, Tadić Tade, Kastelan Zeljko, Librenjak Davor, Gilja Ivan, Vilović Katarina, Kruslin Božo, Kuvezdić Hrvoje

Izvornik
Liječnički vjesnik : glasilo Hrvatskog liječničkog zbora. Suplement (1330-4917) 135 (2013); 292-297

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
Rak mokraćnog mjehura, smjernice
(Bladder cancer, guideline)

Sažetak
Urothelial cancer is the most common bladder cancer. Hematuria is the most common presenting symptom in patients with bladder cancer. The most common diagnostics of bladder cancer is performed by transurethral resection of bladder after which pathohistological diagnosis is set. It is necessary to determine whether the cancer penetrated in muscle layer (muscle-invasive cancer) or not (muscle-noninvasive cancer). Decision on therapeutic modality depends on the clinical stage of disease and on prognostic and risk factors. For muscle non-invasive bladder cancer transurethral resection is preferred with or without intravesical instillation of Bacillus Calmette-Guérin (BCG). For invasive cancer the method of choice is radical cystectomy. Radiotherapy is used in radical and palliative purposes. Metastatic disease is most frequently treated by chemotherapy metotrexate/vinblastine/doxorubicine/cisplatin (MVAC) or gemcitabine/cisplatin (GC). The purpose of this article is to present clinical recommendations to set standards of procedures and criteria in diagnostics, treatment and follow up of patients with bladder cancer in the Republic of Croatia.

Izvorni jezik
Hrvatski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA