Naslov
Is there a place for angiotensin receptor- neprilysin inhibitors in the treatment of heart failure patients after heart transplantation?

Autori
Gulin, Dario ; Planinić, Zrinka ; Čerkez Habek, Jasna ; Šikić, Jozica

Izvornik
Indian Journal of Pharmacology (0253-7613) 51 (2019), 6; 413-415

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Heart failure ; heart transplantation ; sacubitril/valsartan

Sažetak
We present a case report of a heart failure patient after heart transplantation due to end-stage ischemic cardiomyopathy with significant clinical and echocardiographic improvement 3 months after the introduction of sacubitril/valsartan, an angiotensin receptor- neprilysin inhibitor. This new class of drugs is proved to be beneficial in heart failure patients, especially with reduced ejection fraction (HFrEF), but they have not yet been used in heart failure patients after heart transplantation. We believe that the increase of left ventricular systolic function, improvement of global longitudinal strain, and reduction of pulmonary hypertension with consequent clinical recovery in our patient may have been caused by sacubitril/valsartan.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA