Pregled bibliografske jedinice broj: 1149544
Time- and memory-efficient genome assembly with Raven
Time- and memory-efficient genome assembly with Raven // Nature Computational Science, 1 (2021), 332-336 doi:10.1038/s43588-021-00073-4 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 1149544 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Time- and memory-efficient genome assembly with
Raven
Autori
Vaser, Robert ; Šikić, Mile
Izvornik
Nature Computational Science (2662-8457) 1
(2021);
332-336
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
de novo assembly, genome, algorithm
Sažetak
Whole genome sequencing technologies are unable to invariably read DNA molecules intact, a shortcoming that assemblers try to resolve by stitching the obtained fragments back together. Here, we present methods for the improvement of de novo genome assembly from erroneous long reads incorporated into a tool called Raven. Raven maintains similar performance for various genomes and has accuracy on par with other assemblers that support third-generation sequencing data. It is one of the fastest options while having the lowest memory consumption on the majority of benchmarked datasets.
Izvorni jezik
Engleski
Znanstvena područja
Računarstvo
POVEZANOST RADA
Projekti:
HRZZ-IP-2018-01-5886 - De novo sastavljanje genoma i metagenoma (SIGMA) (Šikić, Mile, HRZZ ) ( CroRIS)
Ustanove:
Fakultet elektrotehnike i računarstva, Zagreb
