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Pregled bibliografske jedinice broj: 1148880

Identification of selection signatures on X chromosome in East Adriatic sheep metapopulation


Shihabi, Mario; Lukić, Boris; Držaić, Ivana; Ferenčaković, Maja; Brajković, Vladimir; Vostry, Luboš; Čubrić-Čurik Vlatka; Mikulec, Nataša; Čurik, Ino
Identification of selection signatures on X chromosome in East Adriatic sheep metapopulation // Book of Abstracts of the International Symposium 29th Animal Science days
Gödöllő, Mađarska, 2021. str. 58-58 (poster, međunarodna recenzija, sažetak, znanstveni)


CROSBI ID: 1148880 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Identification of selection signatures on X chromosome in East Adriatic sheep metapopulation

Autori
Shihabi, Mario ; Lukić, Boris ; Držaić, Ivana ; Ferenčaković, Maja ; Brajković, Vladimir ; Vostry, Luboš ; Čubrić-Čurik Vlatka ; Mikulec, Nataša ; Čurik, Ino

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of Abstracts of the International Symposium 29th Animal Science days / - , 2021, 58-58

Skup
International Symposium 29th Animal Science days

Mjesto i datum
Gödöllő, Mađarska, 13.09.2021. - 17.09.2021

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
X chromosome, East Adriatic sheep, selection signatures, female individuals

Sažetak
The sheep is the most important domestic animal in the region East Adriatic. Since strict selection is not practiced, much of the genetic value depends on adaptation to the environment. Therefore, the main objective of this study was to identify genomic regions showing signals of a positive selection signature. Our analysis was based on 200 individuals (males and females) from eighth indigenous breeds (Istrian Sheep, Dalmatian Pramenka ; Dubrovnik Ruda Sheep, Istrian and Pag Island sheep), all representing East Adriatic or the Balkan sheep cluster (by extension meaning) as a single metapopulation, using the Ovine Infinium® HD SNP BeadChip. Our analysis was limited to the X chromosome only (21, 748 SNPs), as such specific studies are rarely performed. Two different methods were used: identification of extremely frequent SNPs in ROHs (eROHi) and Integrated Haplotype Score (iHS). Using iHS, we detected a weak selection signal in a narrow region at position 25.6 Mb, whereas using eROHi (1 Mb), we identified strong selection signals in a large region extending from position 69.9 to 74.6 Mb, with a large number of potential gene candidates, some of which were previously identified in several Chinese and European breeds. Significant gene regions with positive selection signals, most likely related to environmental adaptation, were identified. We have also shown that genotyped rams can contribute to the identification of positive selection signals on the X chromosome.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Poljoprivreda (agronomija), Interdisciplinarne biotehničke znanosti



POVEZANOST RADA


Projekti:
IP-2018-01-8708 - Primjena NGS metoda u procjeni genomske varijabilnosti preživača (ANAGRAMS) (Čubrić Čurik, Vlatka, HRZZ - 2018-01) ( CroRIS)
EK-KF-KK.01.1.1.04.0058 - Potencijal mikroinkapsulacije u proizvodnji sireva (SIR JE IN) (Mikulec, Nataša; Kazazić, Snježana; Zdolec, Nevijo, EK - KK.01.1.1.04) ( CroRIS)

Ustanove:
Agronomski fakultet, Zagreb,
Sveučilište J. J. Strossmayera u Osijeku


Citiraj ovu publikaciju:

Shihabi, Mario; Lukić, Boris; Držaić, Ivana; Ferenčaković, Maja; Brajković, Vladimir; Vostry, Luboš; Čubrić-Čurik Vlatka; Mikulec, Nataša; Čurik, Ino
Identification of selection signatures on X chromosome in East Adriatic sheep metapopulation // Book of Abstracts of the International Symposium 29th Animal Science days
Gödöllő, Mađarska, 2021. str. 58-58 (poster, međunarodna recenzija, sažetak, znanstveni)
Shihabi, M., Lukić, B., Držaić, I., Ferenčaković, M., Brajković, V., Vostry, L., Čubrić-Čurik Vlatka, Mikulec, N. & Čurik, I. (2021) Identification of selection signatures on X chromosome in East Adriatic sheep metapopulation. U: Book of Abstracts of the International Symposium 29th Animal Science days.
@article{article, author = {Shihabi, Mario and Luki\'{c}, Boris and Dr\v{z}ai\'{c}, Ivana and Feren\v{c}akovi\'{c}, Maja and Brajkovi\'{c}, Vladimir and Vostry, Lubo\v{s} and Mikulec, Nata\v{s}a and \v{C}urik, Ino}, year = {2021}, pages = {58-58}, keywords = {X chromosome, East Adriatic sheep, selection signatures, female individuals}, title = {Identification of selection signatures on X chromosome in East Adriatic sheep metapopulation}, keyword = {X chromosome, East Adriatic sheep, selection signatures, female individuals}, publisherplace = {G\"{o}d\"{o}ll\H{o}, Ma\djarska} }
@article{article, author = {Shihabi, Mario and Luki\'{c}, Boris and Dr\v{z}ai\'{c}, Ivana and Feren\v{c}akovi\'{c}, Maja and Brajkovi\'{c}, Vladimir and Vostry, Lubo\v{s} and Mikulec, Nata\v{s}a and \v{C}urik, Ino}, year = {2021}, pages = {58-58}, keywords = {X chromosome, East Adriatic sheep, selection signatures, female individuals}, title = {Identification of selection signatures on X chromosome in East Adriatic sheep metapopulation}, keyword = {X chromosome, East Adriatic sheep, selection signatures, female individuals}, publisherplace = {G\"{o}d\"{o}ll\H{o}, Ma\djarska} }




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