Naslov
Gastrointestinal stability of selenium nanoparticles

Autori
Radić, Kristina ; Vitali Čepo, Dubravka ; Golub, Nikolina ; Štimac, Jelena ; Kalčec, Nikolina ; Vrček, Ena ; Vinković, Tomislav

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, ostalo, znanstveni

Izvornik
UNGAP All-workgroups meeting "Current challenges and future perspectives in oral drug absorption research" / - Leuven, 2021

Skup
UNGAP All-workgroups meeting "Current challenges and future perspectives in oral drug absorption research"

Mjesto i datum
Leuven, Belgija, 28.09.2021. - 29.09.2021

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
selenium nanoparticle ; biogenic synthesis ; gastrointestinal stability

Sažetak
Selenium is one of the essential elements crucial for the normal functioning of the human body. Applied in nano form, it has better pharmacokinetic parameters compared to inorganic forms so the research on the possibilities of using nanoselenium as a dietary supplement is being intensified. However, nanoparticles must have appropriate characteristics in order to ensure satisfactory stability and bioavailability. For this purpose, biologically active natural compounds isolated from biomass or food waste are increasingly used, thus improving the functionality of the obtained nanoparticles and reducing the ecological footprint of the synthesis process. The main objective of this study was to investigate the possibilities of green synthesis of nanoselenium using raw and purified pectins (extracted from mandarin peel and tomato pomace) and olive pomace extract rich in polyphenols. The influence of different synthesis conditions on the size distribution, zeta potential and gastrointestinal stability of the obtained nanoparticles was investigated.

Izvorni jezik
Engleski

Znanstvena područja
Farmacija

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