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Pregled bibliografske jedinice broj: 1147011

FibroScan-ast score predicts 30-day mortality or need for mechanical ventilation among patients hospitalized with COVID-19

Zelenika, Marko; Lucijanić, Marko; Bokun, Tomislav; Božin, Tonći; Barišić Jaman, Mislav; Tješić Drinković, Ida; Paštrović, Frane; Madir, Anita; Lukšić, Ivica; Piskač Živković, Nevenka et al.
FibroScan-ast score predicts 30-day mortality or need for mechanical ventilation among patients hospitalized with COVID-19 // Journal of clinical medicine, 10 (2021), 19; 4355, 12 doi:10.3390/jcm10194355 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 1147011 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
FibroScan-ast score predicts 30-day mortality or need for mechanical ventilation among patients hospitalized with COVID-19

Autori
Zelenika, Marko ; Lucijanić, Marko ; Bokun, Tomislav ; Božin, Tonći ; Barišić Jaman, Mislav ; Tješić Drinković, Ida ; Paštrović, Frane ; Madir, Anita ; Lukšić, Ivica ; Piskač Živković, Nevenka ; Luetić, Krešimir ; Krznarić, Željko ; Ostojić, Rajko ; Filipec Kanižaj, Tajana ; Bogadi, Ivan ; Virović Jukić, Lucija ; Kukla, Michal ; Grgurević, Ivica

Izvornik
Journal of clinical medicine (2077-0383) 10 (2021), 19; 4355, 12

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
COVID-19 ; liver ; non-alcoholic steatohepatitis ; transient elastography ; mortality

Sažetak
Background: Liver involvement in Coronavirus disease 2019 (COVID-19) has been recognised. We aimed to investigate the correlation of non- invasive surrogates of liver steatosis, fibrosis and inflammation using transient elastography (TE) and FibroScan-AST (FAST) score with (a) clinical severity and (b) 30-day composite outcome of mechanical ventilation (MV) or death among patients hospitalized due to COVID-19. Method: Patients with non-critical COVID-19 at admission were included. Liver stiffness measurement (LSM) and controlled attenuation parameter (CAP) were assessed by TE. Clinical severity of COVID-19 was assessed by 4C Mortality Score (4CMS) and need for high-flow nasal cannula (HFNC) oxygen supplementation. Results: 217 patients were included (66.5% males, median age 65 years, 4.6% with history of chronic liver disease). Twenty- four (11.1%) patients met the 30-day composite outcome. Median LSM, CAP and FAST score were 5.2 kPa, 274 dB/m and 0.31, respectively, and neither was associated with clinical severity of COVID-19 at admission. In multivariate analysis FAST > 0.36 (OR 3.19, p = 0.036), 4CMS (OR 1.68, p = 0.002) and HFNC (OR 7.03, p = 0.001) were independent predictors of adverse composite outcome. Conclusion: Whereas LSM and CAP failed to show correlation with COVID-19 severity and outcomes, FAST score was an independent risk factor for 30- day mortality or need for MV.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA

Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb,
Klinička bolnica "Merkur",
Medicinski fakultet, Zagreb,
Klinička bolnica "Sveti Duh",
KBC "Sestre Milosrdnice",
Klinička bolnica "Dubrava",
Klinički bolnički centar Zagreb

Profili:

Avatar Url Rajko Ostojić (autor)

Avatar Url Nevenka Piskać Živković (autor)

Avatar Url Anita Madir (autor)

Avatar Url Tomislav Bokun (autor)

Avatar Url Mislav Barišić-Jaman (autor)

Avatar Url Lucija Virović Jukić (autor)

Avatar Url Frane Paštrović (autor)

Avatar Url Željko Krznarić (autor)

Avatar Url Krešimir Luetić (autor)

Avatar Url Tajana Filipec Kanižaj (autor)

Avatar Url Ivica Lukšić (autor)

Avatar Url Marko Lucijanic (autor)

Avatar Url Ivica Grgurević (autor)

Poveznice na cjeloviti tekst rada:

doi

Citiraj ovu publikaciju:

Zelenika, Marko; Lucijanić, Marko; Bokun, Tomislav; Božin, Tonći; Barišić Jaman, Mislav; Tješić Drinković, Ida; Paštrović, Frane; Madir, Anita; Lukšić, Ivica; Piskač Živković, Nevenka et al.
FibroScan-ast score predicts 30-day mortality or need for mechanical ventilation among patients hospitalized with COVID-19 // Journal of clinical medicine, 10 (2021), 19; 4355, 12 doi:10.3390/jcm10194355 (međunarodna recenzija, članak, znanstveni)
Zelenika, M., Lucijanić, M., Bokun, T., Božin, T., Barišić Jaman, M., Tješić Drinković, I., Paštrović, F., Madir, A., Lukšić, I. & Piskač Živković, N. (2021) FibroScan-ast score predicts 30-day mortality or need for mechanical ventilation among patients hospitalized with COVID-19. Journal of clinical medicine, 10 (19), 4355, 12 doi:10.3390/jcm10194355.
@article{article, author = {Zelenika, Marko and Lucijani\'{c}, Marko and Bokun, Tomislav and Bo\v{z}in, Ton\'{c}i and Bari\v{s}i\'{c} Jaman, Mislav and Tje\v{s}i\'{c} Drinkovi\'{c}, Ida and Pa\v{s}trovi\'{c}, Frane and Madir, Anita and Luk\v{s}i\'{c}, Ivica and Piska\v{c} \v{Z}ivkovi\'{c}, Nevenka and Lueti\'{c}, Kre\v{s}imir and Krznari\'{c}, \v{Z}eljko and Ostoji\'{c}, Rajko and Filipec Kani\v{z}aj, Tajana and Bogadi, Ivan and Virovi\'{c} Juki\'{c}, Lucija and Kukla, Michal and Grgurevi\'{c}, Ivica}, year = {2021}, pages = {12}, DOI = {10.3390/jcm10194355}, chapter = {4355}, keywords = {COVID-19, liver, non-alcoholic steatohepatitis, transient elastography, mortality}, journal = {Journal of clinical medicine}, doi = {10.3390/jcm10194355}, volume = {10}, number = {19}, issn = {2077-0383}, title = {FibroScan-ast score predicts 30-day mortality or need for mechanical ventilation among patients hospitalized with COVID-19}, keyword = {COVID-19, liver, non-alcoholic steatohepatitis, transient elastography, mortality}, chapternumber = {4355} }
@article{article, author = {Zelenika, Marko and Lucijani\'{c}, Marko and Bokun, Tomislav and Bo\v{z}in, Ton\'{c}i and Bari\v{s}i\'{c} Jaman, Mislav and Tje\v{s}i\'{c} Drinkovi\'{c}, Ida and Pa\v{s}trovi\'{c}, Frane and Madir, Anita and Luk\v{s}i\'{c}, Ivica and Piska\v{c} \v{Z}ivkovi\'{c}, Nevenka and Lueti\'{c}, Kre\v{s}imir and Krznari\'{c}, \v{Z}eljko and Ostoji\'{c}, Rajko and Filipec Kani\v{z}aj, Tajana and Bogadi, Ivan and Virovi\'{c} Juki\'{c}, Lucija and Kukla, Michal and Grgurevi\'{c}, Ivica}, year = {2021}, pages = {12}, DOI = {10.3390/jcm10194355}, chapter = {4355}, keywords = {COVID-19, liver, non-alcoholic steatohepatitis, transient elastography, mortality}, journal = {Journal of clinical medicine}, doi = {10.3390/jcm10194355}, volume = {10}, number = {19}, issn = {2077-0383}, title = {FibroScan-ast score predicts 30-day mortality or need for mechanical ventilation among patients hospitalized with COVID-19}, keyword = {COVID-19, liver, non-alcoholic steatohepatitis, transient elastography, mortality}, chapternumber = {4355} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus

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