Naslov
Characterisation of 1,4-disubstituted 2,5- diketopiperazines by ESI mass spectrometry

Autori
Veljković, Filip ; Masnikosa, Romana ; Perić, Berislav ; Pantalon Juraj, Natalija ; Georgijević, Jelena ; Kirin, Srećko I. ; Veličković, Suzana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Physical Chemistry 2021 : 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry: Book of Abstracts / - , 2021, 129-129

Skup
15th International Conference on Fundamental and Applied Aspects of Physical Chemistry

Mjesto i datum
Beograd, Srbija, 20.09.2021. - 24.09.2021

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
2, 5-diketopiperazines ; mass spectrometry

Sažetak
The diketopiperazines have been steadily attracting researchers’ attention in pharmaceutical chemistry due to their potential biological effects. Electrospray ionization mass spectrometry (ESI MS) is known to be a versatile analytical technique for detection of very low concentrations of various diketopiperazines in different samples. Hence, we characterized our p-disubstituted phenyldiketopiperazines 1 ( R = H ), 2 ( R = NO2 ) and 3 ( R = -N(CH3) ) by ESI MS. We have shown that the majority of the fragment ions in the ESI mass spectra originated from reactions initiated by one of the nitrogen atoms of the piperazine ring.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

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