Naslov
Oxidative stress induced by orthodontic treatment and supportive antioxidant therapy

Autori
Primožič, Jasmina ; Poljšak, Borut ; Jamnik, Polona ; Kovač, Vito ; Čanadi Jurešić, Gordana ; Špalj, Stjepan

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni

Skup
2nd Congress of Faculty of Dental Medicine University of Rijeka

Mjesto i datum
Rijeka, Hrvatska, 02.09.2021. - 03.09.2021

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
oxidative stress ; antioxidans ; metal ; orthodontics

Sažetak
The estimation of the health risk due to the amount of heavy metals released and the level of selected oxidative stress parameters generated during treatment with fixed orthodontic appliances is presented based on sistematic review of literature. The estimated health risk is a minor one, as only very high metal concentrations induce cytotoxicity and oxidative stress, which was found in the studies on cell cultures. On the other hand, several studies reported that orthodontic treatment can induce transient imbalance in the ratio between oxidants and antioxidants in saliva as well as at the systemic level of clinically healthy subjects. The increased reactive oxygen species levels can occur at a local level in the oral cavity, which could pose a problem to patients with lower efficiency of endogenous antioxidant defense systems. Metal chelating antioxidants (transferrin, albumin, ceruloplasmin, flavinoids) could be used to prevent radical formation by metal ions from orthodontic appliances.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Dentalna medicina

Napomena
Funded by Croatian Science Foundation and
Slovenian Research Agency „Determining the
incidence, causes and harmful effects of oxidative
stress caused by the use of fixed orthodontic
appliances“ (No. IPS-2020-01 and P3-0388, J3-2523)

POVEZANOST RADA