Naslov
Funkcionalizacija magnetnih nanočestica za dostavu lijekova: sinteza i karakterizacija
(FUNCTIONALIZED MAGNETITE NANOPARTICLES FOR DRUG DELIVERY: SYNTHESIS AND CHARACTERIZATION METHODS)

Autori
Mandić, Lucija ; Sadžak, Anja ; Šegota, Suzana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
XIII. SUSRET MLADIH KEMIJSKIH INŽENJERA KNJIGA SAŽETAKA / - , 2020, 51-51

Skup
XIII. susret mladih kemijskih inženjera (SMLKI 2020)

Mjesto i datum
Zagreb, Hrvatska, 20.02.2020. - 21.02.2020

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Podatak o recenziji nije dostupan

Ključne riječi
superparamagnetske nanočestice ; flavonoidi ; dostava lijekova
(superparamagnetic nanoparticles ; flavonoids ; drug delivery)

Sažetak
Magnetic nanostructured materials, especially Fe3O4 nanoparticles, have many potential applications ranging from nanoelectronics to biomedical applications. These nanoparticles are widely used in biomedical applications as a drug delivery, drug targeting, bio-separation techniques, contrast agents for the magnetic resonance imaging systems, and as heating intermediates for the therapy of cancer or hyperthermia which is mainly attributed to their excellent optical, magnetic and biological characteristics. Iron oxide nanoparticles were synthesized by a solvothermal method. To enhance the surface functionality, the synthesized nanoparticles were stabilized by coating with polyethylene glycol (PEG-4000), a biodegradable and biocompatible polymer. Both bare and PEG-4000 coated iron oxide particles were characterized by various techniques (X-ray diffraction (XRPD), scanning electron microscopy (SEM), dynamic light scattering (DLS), and Fourier transform infrared spectroscopy (FTIR) to evaluate their structural, morphological and physicochemical suitability for drug delivery applications. The results confirmed that the mesoporous magnetite nanoparticles could be an universal, stable and excellent material for drug delivery application.

Izvorni jezik
Engleski

Znanstvena područja
Kemijsko inženjerstvo

POVEZANOST RADA