Pregled bibliografske jedinice broj: 1141912
Extraction methods for chromatographic analysis of pharmaceuticals in environment
Extraction methods for chromatographic analysis of pharmaceuticals in environment // 2nd Global Virtual Conference on Pharmaceutical Sciences and Drug Development, Research and Advancements in Pharmaceutical Biotechnology and Drug Delivery Systems
online; konferencija, 2021. str. 12-12 (predavanje, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 1141912 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Extraction methods for chromatographic analysis of
pharmaceuticals in environment
Autori
Ašperger, Danijela ; Babić, Bruna ; Cerić, Dijana
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
2nd Global Virtual Conference on Pharmaceutical Sciences and Drug Development, Research and Advancements in Pharmaceutical Biotechnology and Drug Delivery Systems
/ - , 2021, 12-12
Skup
2nd Global Virtual Conference on Pharmaceutical Sciences and Drug Development
Mjesto i datum
Online; konferencija, 09.08.2021. - 10.08.2021
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
pharmaceuticals, extraction, high performance liquid chromatography, USE, MSPD
Sažetak
Pharmaceuticals are substances that are used in human and veterinary practice and are so-called emerging contaminants. Their occurrence in the environment is still not law regulated, while certain numbers of published articles record their negative impact on human health. From the literature overview, pharmaceuticals were determined in different environment samples like water, sludge, soil, manure and sediment. In this work pharmaceuticals who belong to different structure groups were determined in sludge and sediment sample and following five extractions were developed and optimized: EA, USE, MAE, MSPD and PSE. Chosen pharmaceuticals were macrolide antibiotic tylosine, antihelmintics albendazole, febantel and levamisole, anesthetics lidocaine and procaine and glucocorticoids hydrocortisone and dexamethasone. Pharmaceutical concentrations extracted from sediment sample were determined by high performance liquid chromatography using diode array detector. After chromatographic analysis, all methods were validated and the following optimal parameters were determined for each extraction method: sludge and sediment mass, solvent, contact time between sludge/sediment and solvent, extraction duration, agitation frequency and extraction temperature (EA) ; solvent, extraction duration, power and temperature of ultrasonic bath (USE) ; solvent, extraction duration, temperature, solvent volume (MAE) ; sorbent, solvent, solvent volume, sediment/sorbent mass ratio (MSPD) ; solvent (PLE).
Izvorni jezik
Engleski
Znanstvena područja
Kemijsko inženjerstvo
