Pregled bibliografske jedinice broj: 1138143
What have we learned about antinociceptive effect of botulinum toxin type A from mirror-image pain models?
What have we learned about antinociceptive effect of botulinum toxin type A from mirror-image pain models? // Toxicon, 185 (2020), 164-173 doi:10.1016/j.toxicon.2020.07.014 (međunarodna recenzija, članak, znanstveni)
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Naslov
What have we learned about antinociceptive effect
of botulinum toxin type A from mirror-image pain
models?
Autori
Drinovac Vlah, Višnja ; Bach-Rojecky, Lidija
Izvornik
Toxicon (0041-0101) 185
(2020);
164-173
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
bilateral antinociceptive effect ; botulinum neurotoxin type A ; mirror pain ; synaptosomal-associated protein of 25 kDa
Sažetak
Mirror pain represents pain with complex pathophysiological background experienced at both sides of the body, usually after unilateral injury. Although observed almost 10 years ago, the phenomenon of bilateral antinociceptive effect of botulinum toxin type A (BoNT/A) following its unilateral administration in experimental mirror- image pain (MP) models remains challenging and intriguing task to explain. Data generated so far using MP models and mechanisms behind this unique feature of BoNT/A might influence the overall understanding of its mechanism of antinociceptive action. Here we review the effects contributing to BoNT/A's bilateral antinociceptive action observed in experimental MP models.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti, Farmacija
POVEZANOST RADA
Projekti:
IP-2014-09-4503 - Klostridijski neurotoksini i mozak (BrainTox) (Lackovic, Zdravko, HRZZ - 2014-09) ( CroRIS)
Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE