Naslov
STRONTIUM AND MAGNESIUM COSUBSTITUTED HYDROXYAPATITE/WHITLOCKITE SCAFFOLDS SYNTHESIZED FROM CUTTLEFISH BONE

Autori
Bauer, Leonard ; Antunović, Maja ; Ivanković, Marica ; Ivanković, Hrvoje

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
MATRIB 2021. Materials, Tribology and Recycling. Proceedings / Ćorić, Danko ; Šolić, Sanja ; Ivušić, Franjo - Zagreb : Hrvatsko društvo za materijale i tribologiju (HDMT), 2021, 55-75

Skup
21th International Conference on Materials (MATRIB 2021)

Mjesto i datum
Vela Luka, Hrvatska, 30.06.2021. - 02.07.2021

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
strontium, magnesium, hydroxyapatite, whitlockite, bone scaffold, unit cell parematers

Sažetak
Strontium substituted and strontium- and magnesium-cosubstituted calcium phosphate highly porous scaffolds based on hydroxyapatite (HAp, Ca10(PO4)6(OH)2) were hydrothermally synthesized from aragonite cuttlefish bone. In situ addition of Sr2+ ion resulted in a total conversion of aragonite precursor to HAp. At maximal examined addition of strontium (10 mol.% Sr2+ instead of Ca2+) whitlockite (WH, Ca18MgxSry(HPO4)2(PO4)12) appeared with up to 2 mas.%. Strontium showed no effect on HAp unit cell parameters. In situ cosubstitution resulted with scaffolds which showed that Mg2+ ions have a significant effect on HAp/WH ratio and surface agglomerates size, while Sr2+ ions have a great influence on WH unite cell parameters. In vitro cell culture confirmed that scaffolds are not cytotoxic. Prepared cosubstituted carbonated HAp/WH scaffolds indicate to have great potential to be used as bone scaffolds where incorporation of Sr2+ and Mg2+ ions into crystallographic structure can improve biological response.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija, Kemijsko inženjerstvo

POVEZANOST RADA