Naslov
In regard to Lee et al

Autori
Murgić, Jure ; Grgurević, Lovorka ; Grazio, Simeon ; Vukojević, Rudolf ; Hoxha, Nita ; Marić-Brozić, Jasmina ; Soldić, Željko ; Zovak, Mario ; Fröbe, Ana

Izvornik
International journal of radiation oncology, biology, physics (0360-3016) 108 (2020), 5; 1392-1394

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, komentar, stručni

Ključne riječi
study by Lee et al ; effect of radiation therapy ; progressive posttraumatic heterotopic ossification (HO) ; hypofractionated RT

Sažetak
We read with interest the recent study by Lee et al. The authors examined the effect of radiation therapy (RT) in 9 patients with progressive posttraumatic heterotopic ossification (HO).1 They reported reduction of HO formations coupled with reduced pain and improved ambulatory status in majority of patients treated with hypofractionated RT. This could potentially shed light on the difference in radiation and fractionation sensitivity between these 2 mainstays of HO because our experience demonstrates that extremely low doses (biologically equivalent dose 3 <5 Gy), contrary to the theory of mesenchymal stem cell radioresistance, 7 yielded lasting therapeutic effect.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

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