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Pregled bibliografske jedinice broj: 1134432

Carnosine, small but mighty - prospect of use as functional ingredient for functional food formulation

Jukić, Ivana; Kolobarić, Nikolina; Stupin, Ana; Matić, Anita; Kozina, Nataša; Mihaljevič, Zrinka; Mihalj, Martina; Šušnjara, Petar; Stupin, Marko; Breškić Ćurić, Željka et al.
Carnosine, small but mighty - prospect of use as functional ingredient for functional food formulation // Antioxidants, 10 (2021), 7; 1037, 31 doi:10.3390/antiox10071037 (međunarodna recenzija, pregledni rad, znanstveni)

CROSBI ID: 1134432 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Carnosine, small but mighty - prospect of use as functional ingredient for functional food formulation

Autori
Jukić, Ivana ; Kolobarić, Nikolina ; Stupin, Ana ; Matić, Anita ; Kozina, Nataša ; Mihaljevič, Zrinka ; Mihalj, Martina ; Šušnjara, Petar ; Stupin, Marko ; Breškić Ćurić, Željka ; Selthofer-Relatić, Kristina ; Kibel, Aleksandar ; Lukinac, Anamarija ; Kolar, Luka ; Kralik, Gordana ; Kralik, Zlata ; Szechenyi, Aleksandar ; Jozanović, Marija ; Galović, Olivera ; Medvidović-Kosanović, Martina ; Drenjančević, Ines

Izvornik
Antioxidants (2076-3921) 10 (2021), 7; 1037, 31

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
oxidative stress ; antioxidants ; functional food ; carnosine

Sažetak
Carnosine is a dipeptide synthesized in the body from β-alanine and L-histidine. It is found in high concentrations in the brain, muscle, and gastrointestinal tissues of humans and is present in all vertebrates. Carnosine has a number of beneficial antioxidant properties. For example, carnosine scavenges reactive oxygen species (ROS) as well as alpha- beta unsaturated aldehydes created by peroxidation of fatty acid cell membranes during oxidative stress. Carnosine can oppose glycation, and it can chelate divalent metal ions. Carnosine alleviates diabetic nephropathy by protecting podocyte and mesangial cells, and can slow down aging. Its component, the amino acid beta-alanine, is particularly interesting as a dietary supplement for athletes because it increases muscle carnosine, and improves effectiveness of exercise and stimulation and contraction in muscles. Carnosine is widely used among athletes in the form of supplements, but rarely in the population of cardiovascular or diabetic patients. Much less is known, if any, about its potential use in enriched food. In the present review, we aimed to provide recent knowledge on carnosine properties and distribution, its metabolism (synthesis and degradation), and analytical methods for carnosine determination, since one of the difficulties is the measurement of carnosine concentration in human samples. Furthermore, the potential mechanisms of carnosine’s biological effects in musculature, metabolism and on immunomodulation are discussed. Finally, this review provides a section on carnosine supplementation in the form of functional food and potential health benefits and up to the present, neglected clinical use of carnosine.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Temeljne medicinske znanosti, Prehrambena tehnologija



POVEZANOST RADA

Ustanove:
Fakultet agrobiotehničkih znanosti Osijek,
Klinički bolnički centar Osijek,
Medicinski fakultet, Osijek,
Sveučilište u Osijeku - Odjel za kemiju,
Fakultet za dentalnu medicinu i zdravstvo, Osijek

Profili:

Avatar Url Zrinka Mihaljević (autor)

Avatar Url Aleksandar Kibel (autor)

Avatar Url Ivana Jukić (autor)

Avatar Url Zlata Kralik (autor)

Avatar Url Olivera Galović (autor)

Avatar Url Kristina Selthofer-Relatić (autor)

Avatar Url Anita Matić (autor)

Avatar Url Nataša Kozina (autor)

Avatar Url Martina Medvidović Kosanović (autor)

Avatar Url Ines Drenjančević (autor)

Avatar Url Aleksandar Secenji (autor)

Avatar Url Marko Stupin (autor)

Avatar Url Martina Mihalj (autor)

Avatar Url Ana Stupin (autor)

Avatar Url Nikolina Bilić-Dujmušić (autor)

Avatar Url Petar Šušnjara (autor)

Avatar Url Gordana Kralik (autor)

Avatar Url Marija Jozanović (autor)

Poveznice na cjeloviti tekst rada:

Pristup cjelovitom tekstu rada doi www.mdpi.com doi.org

Citiraj ovu publikaciju:

Jukić, Ivana; Kolobarić, Nikolina; Stupin, Ana; Matić, Anita; Kozina, Nataša; Mihaljevič, Zrinka; Mihalj, Martina; Šušnjara, Petar; Stupin, Marko; Breškić Ćurić, Željka et al.
Carnosine, small but mighty - prospect of use as functional ingredient for functional food formulation // Antioxidants, 10 (2021), 7; 1037, 31 doi:10.3390/antiox10071037 (međunarodna recenzija, pregledni rad, znanstveni)
Jukić, I., Kolobarić, N., Stupin, A., Matić, A., Kozina, N., Mihaljevič, Z., Mihalj, M., Šušnjara, P., Stupin, M. & Breškić Ćurić, Ž. (2021) Carnosine, small but mighty - prospect of use as functional ingredient for functional food formulation. Antioxidants, 10 (7), 1037, 31 doi:10.3390/antiox10071037.
@article{article, author = {Juki\'{c}, Ivana and Kolobari\'{c}, Nikolina and Stupin, Ana and Mati\'{c}, Anita and Kozina, Nata\v{s}a and Mihaljevi\v{c}, Zrinka and Mihalj, Martina and \v{S}u\v{s}njara, Petar and Stupin, Marko and Bre\v{s}ki\'{c} \'{C}uri\'{c}, \v{Z}eljka and Selthofer-Relati\'{c}, Kristina and Kibel, Aleksandar and Lukinac, Anamarija and Kolar, Luka and Kralik, Gordana and Kralik, Zlata and Szechenyi, Aleksandar and Jozanovi\'{c}, Marija and Galovi\'{c}, Olivera and Medvidovi\'{c}-Kosanovi\'{c}, Martina and Drenjan\v{c}evi\'{c}, Ines}, year = {2021}, pages = {31}, DOI = {10.3390/antiox10071037}, chapter = {1037}, keywords = {oxidative stress, antioxidants, functional food, carnosine}, journal = {Antioxidants}, doi = {10.3390/antiox10071037}, volume = {10}, number = {7}, issn = {2076-3921}, title = {Carnosine, small but mighty - prospect of use as functional ingredient for functional food formulation}, keyword = {oxidative stress, antioxidants, functional food, carnosine}, chapternumber = {1037} }
@article{article, author = {Juki\'{c}, Ivana and Kolobari\'{c}, Nikolina and Stupin, Ana and Mati\'{c}, Anita and Kozina, Nata\v{s}a and Mihaljevi\v{c}, Zrinka and Mihalj, Martina and \v{S}u\v{s}njara, Petar and Stupin, Marko and Bre\v{s}ki\'{c} \'{C}uri\'{c}, \v{Z}eljka and Selthofer-Relati\'{c}, Kristina and Kibel, Aleksandar and Lukinac, Anamarija and Kolar, Luka and Kralik, Gordana and Kralik, Zlata and Szechenyi, Aleksandar and Jozanovi\'{c}, Marija and Galovi\'{c}, Olivera and Medvidovi\'{c}-Kosanovi\'{c}, Martina and Drenjan\v{c}evi\'{c}, Ines}, year = {2021}, pages = {31}, DOI = {10.3390/antiox10071037}, chapter = {1037}, keywords = {oxidative stress, antioxidants, functional food, carnosine}, journal = {Antioxidants}, doi = {10.3390/antiox10071037}, volume = {10}, number = {7}, issn = {2076-3921}, title = {Carnosine, small but mighty - prospect of use as functional ingredient for functional food formulation}, keyword = {oxidative stress, antioxidants, functional food, carnosine}, chapternumber = {1037} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus

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