Pregled bibliografske jedinice broj: 1127989
Evaluation of Apoptotic, Antiproliferative, and Antimigratory Activity of Origanum syriacum against Metastatic Colon Cancer Cells
Evaluation of Apoptotic, Antiproliferative, and Antimigratory Activity of Origanum syriacum against Metastatic Colon Cancer Cells // Journal of Herbs, Spices & Medicinal Plants, 25 (2019), 3; 202-217 doi:10.1080/10496475.2019.1587674 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 1127989 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Evaluation of Apoptotic, Antiproliferative, and
Antimigratory Activity of Origanum syriacum
against Metastatic Colon Cancer Cells
Autori
Aldisi, Sara S. ; Jaganjac, Morana ; Eid, Ali H. ; Goktepe, Ipek
Izvornik
Journal of Herbs, Spices & Medicinal Plants (1049-6475) 25
(2019), 3;
202-217
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Lovo and SW620 cells ; ethanol extract ; herbal medicine ; Mediterranean
Sažetak
The effect of an ethanolic extract of fresh leaves of Origanum syriacum (OSEE) on the proliferative, apoptotic, and migratory capacities of LoVo and SW620 colon cancer cells was investigated. OSEE showed a concentration- dependent apoptotic and antiproliferative effect on LoVo and SW620 cells at 500 μg mL−1 or higher after 48 h of exposure. Additionally, OSEE inhibited the migration of both LoVo and SW620 cells by decreasing (50–75%) wound- healing capacity at 500 and 1, 000 μg mL−1. The results suggest that OSEE may have potential anticarcinogenic activity in metastatic colon cancer cells through the dual effect of inhibiting cell proliferation and migration and induction of apoptosis.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
Citiraj ovu publikaciju:
Časopis indeksira:
- Scopus
