Pregled bibliografske jedinice broj: 1127676
Molecular detection of colorectal cancer
Molecular detection of colorectal cancer, 2021. doi:10.3390/ijms22094327 (natuknica u enciklopediji, leksikonu, rječniku i sl.).
CROSBI ID: 1127676 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Molecular detection of colorectal cancer
Autori
Verbanac, Donatella ; Čeri, Andrea ; Hlapčić, Iva ; Shakibaei, Mehdi ; Brockmueller, Aranka ; Krušlin, Božo ; Ljubičić, Neven ; Baršić, Neven ; Detel, Dijana ; Batičić, Lara ; Rumora, Lada ; Somborac-Bačura, Anita ; Štefanović, Mario ; Ćelap, Ivana ; Demirović, Alma ; Petlevski, Roberta ; Petrik, József ; Grdić Rajković, Marija ; Hulina-Tomašković, Andrea ; Rako, Ivana ; Saso, Luciano ; Barišić, Karmela
Izvornik
Scholarly community encyclopedia
Vrsta, podvrsta
Ostale vrste radova, natuknica u enciklopediji, leksikonu, rječniku i sl.
Godina
2021
Ključne riječi
biomarkers ; colorectal cancer ; early detection examination ; liquid biopsy ; personalized medicine ; tumor treatment ; exosomes ; ctDNA ; CTC
Sažetak
Drug-specific therapeutic approaches for colorectal cancer (CRC) have contributed to a significant improvement in the health status of patients. However, a great need to improve personalization of treatments based on genetic and epigenetic tumor profiles to maximize quality and efficacy while limiting cytotoxicity remains. Currently, CEA and CA 19- 9 are the only validated blood biomarkers in clinical practice. For this reason, laboratories are trying to identify new specific prognostic and, more importantly, predictive biomarkers for CRC patient profiles. Thus, the unique landscape of personalized biomarker data should have a clinical impact on CRC treatment strategies and molecular genetic screening tests should become the standard method for CRC diagnosis, as well as detection of disease progression.
Izvorni jezik
Engleski
Znanstvena područja
Biologija, Interdisciplinarne prirodne znanosti, Temeljne medicinske znanosti, Kliničke medicinske znanosti, Farmacija
POVEZANOST RADA
Projekti:
IP-2019-04-4624 - Gensko, proteinsko i RNA profiliranje kolorektalnog karcinoma primjenom tekuće biopsije (CRCMolProfil) (Barišić, Karmela, HRZZ - 2019-04) ( CroRIS)
Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb,
Medicinski fakultet, Rijeka,
Stomatološki fakultet, Zagreb,
Medicinski fakultet, Zagreb,
KBC "Sestre Milosrdnice",
Klinički bolnički centar Zagreb
Profili:
Ivana Rako
(autor)
Ivana Ćelap
(autor)
Neven Baršić
(autor)
Andrea Hulina Tomašković
(autor)
Neven Ljubičić
(autor)
Božo Krušlin
(autor)
Andrea Čeri
(autor)
Roberta Petlevski
(autor)
Anita Somborac Bačura
(autor)
Mario Štefanović
(autor)
Iva Hlapčić
(autor)
Alma Demirović
(autor)
Jozsef Petrik
(autor)
Donatella Verbanac
(autor)
Lara Batičić
(autor)
Dijana Detel
(autor)
Lada Rumora
(autor)
Karmela Barišić
(autor)
Marija Grdić Rajković
(autor)