Naslov
Determination of N-acetyl-cysteine by flow-injection potentiometry

Autori
Radić, Njegomir ; Komljenović, Josipa

Izvornik
Fresenius journal of analytical chemistry (0937-0633) 360 (1998), 6; 675-678

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
flow-injection potentiometry; tubular sensor; N-acetylcysteine

Sažetak
A multi-purpose tubular flow-through sensor was constructed with an AgI-based membrane. The membrane was prepared by pressing silver salts (AgI, Ag_2S) and powdered Teflon. This membrane was incorporated in the tubular flow-through sensor body. A 2-mm diameter hole was drilled through the center of the tubular sensor and the membrane, thus determining the active sensor volume of about 4 microL. The tubular sensor with reference electrode was placed into a complex flow-injection sy! stem and used for the flow-through determination of N-acetyl-L-cysteine, (NAC), in perchloric acid medium, pH=1. Linear dependence was established between the recorded signal height and the concentration of NAC in the injected sample. The recorded change in potential for a decade change in concentration, 62 mV {;p(NAC)};^-1, in the concentration range from 1×10^-4 to 1×10^-1 M, was based on the formation mechanism of the sparingly soluble deposit between silver and NAC on the surface of the sensitive part of the membrane.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA