Pregled bibliografske jedinice broj: 1111321
Chronic kidney disease and cardiovascular mortality in patients with atrial fibrillation European Society of Hypertension project – ESH A Fib
Chronic kidney disease and cardiovascular mortality in patients with atrial fibrillation European Society of Hypertension project – ESH A Fib // Medicine, 100 (2021), e23975, 8 doi:10.1097/MD.0000000000023975 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 1111321 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Chronic kidney disease and cardiovascular mortality in patients with atrial fibrillation European Society
of Hypertension project – ESH A Fib
(Chronic kidney disease and cardiovascular mortality in patients with atrial fibrillation European Society of
Hypertension project – ESH A Fib)
Autori
Premužić, Vedran ; Stevanović, Ranko ; Radić, Petra ; Salvetti, Massimo ; Lovrić Benčić, Martina ; Jelaković, Ana ; Miličić, Davor ; Capak, Krunoslav ; Agabiti-Rosei, Enrico ; Jelaković, Bojan
Izvornik
Medicine (0025-7974) 100
(2021);
E23975, 8
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
atrial fibrillation ; cardiovascular mortality ; chronic kidney disease ; renal impairment
Sažetak
Our aim was to analyze characteristics of atrial fibrillation (AF) patients with chronic kidney disease (CKD) from the Croatian cohort of the ESH A Fib survey and to determine the association of estimated glomerular filtration rate (eGFR) with cardiovascular (CV) mortality after 24 months of follow-up. Consecutive sample of 301 patients with AF were enrolled in the period 2014 to 2018. Hypertension was defined as BP >140/90 mm Hg and/or antihypertensive drugs treatment, CKD was defined as eGFR (CKD Epi) <60ml/min/1.73m2 which was confirmed after 3 months. CKD was diagnosed in 45.2% of patients (13.3% in CKD stage >3b). CKD patients were older than non-CKD and had significantly more frequent coronary heart disease, heart failure and valvular disease. CKD patients had significantly higher CHA2DS2-VASc score and more CKD than non-CKD patients had CHA2DS2-VASc >2. Crude CV mortality rate per 1000 population at the end of the first year of the follow-up was significantly higher in CKD vs non- CKD group who had shorter mean survival time. CV mortality was independently associated with eGFR, male gender, CHA2DS2VASc and R2CHA2DS2VASc scores. Prevalence of CKD, particularly more advanced stages of CKD, is very high in patients with AF. Observed higher CV mortality and shorter mean survival time in CKD patients could be explained with higher CHA2DS2VASc score which is a consequence of clustering of all score components in CKD patients. However, eGFR was independently associated with CV mortality. In our cohort, R2CHA2DS2VASc score was not associated significantly more with CV mortality than CHA2DS2VASc score.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Ustanove:
Hrvatski zavod za javno zdravstvo,
Medicinski fakultet, Zagreb,
KBC "Sestre Milosrdnice"
Profili:
Davor Miličić
(autor)
Vedran Premužić
(autor)
Martina Lovrić Benčić
(autor)
Ranko Stevanović
(autor)
Bojan Jelaković
(autor)
Petra Radić
(autor)
Krunoslav Capak
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE