Naslov
Renal vascular resistance in diabetic nephropathy : duplex Doppler US evaluation

Autori
Brkljačić, Boris ; Mrzljak, Vladimir ; Drinković, Ivan ; Soldo, Dragica ; Sabljar-Matovinović, Mirjana ; Hebrang, Andrija

Izvornik
Radiology (0033-8419) 192 (1994), 2; 549-554

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
diabetes mellitus ; kidney ; renal arteries ; US

Sažetak
Purpose: to evaluate duplex Doppler sonography to assess renal vascular resistance (RVR) in diabetic patients. Resistive indexes (RIs) and pulsatility indexes (PIs) were measured in intrarenal arteries of 144 patients with diabetes mellitus and 61 control subjects. RIs and PIs were compared for control subjects and patients with diabetic nephropathy and correlated with laboratory and clinical findings. In control subjects, the mean RI was 0.595 +/- 0.033 (standard deviation) and mean PI was 1.001 +/- 0.105. Elevated RIs and PIs accompanied progression of nephropathy. Statistically significant (P < .001) correlations were observed between both RI and PI and serum creatinine level, creatinine clearance rate, systolic and diastolic blood pressure measurements, and patient age. Doppler indexes reflect increased RVR in diabetic nephropathy and correlate with laboratory and clinical parameters, but RI and PI measurements offer no advantages over these parameters to predict disease progress or in patient care.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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