Naslov
Antibiotic susceptibility of bacterial isolates from dogs with respiratory disease

Autori
Štritof, Zrinka ; Matić, Renata ; Hađina, Suzana ; Habuš, Josipa ; Pintarić, Selma ; Perharić, Matko ; Cvetnić, Marija

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
FEMS Online Conference on Microbiology: Electronic Abstract Book / - , 2021, 5-5

Skup
FEMS Online Conference on Microbiology

Mjesto i datum
Beograd, Srbija; online, 28.10.2020. - 31.10.2020

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
Antibiotic ; Susceptibility ; Respiratory ;

Sažetak
Background: Performing regular cultures and sensitivity testing keeps veterinarians familiar with local resistance patterns and enhances empirical choice of antimicrobial therapy. Objectives: The aim of this study was to investigate the prevalence of bacterial species isolated from dogs with respiratory signs and analyze antibiotic sensitivity of isolates. Methods: Clinical samples from dogs with respiratory signs submitted for bacterial culture were included in the study. Bacterial species were identified following standard laboratory procedures and antimicrobial susceptibility testing (AST) was performed using disc diffusion method according to the EUCAST guidelines. Results: Out of 177 clinical samples, 128 (72.3%) were culture-positive. Most often isolated bacteria were B. bronchiseptica (28.1 %), S. pseudintermedius (27.3 %) and E. coli (18.0 %). Isolates of B. bronchiseptica showed highest susceptibility to gentamycin (97.0 %), followed by enrofloxacin (90.6 %), tetracyclines (63.3 %), amoxicillin/clavulanic acid (10.0 %), ampicillin (8.1 %) and trimethoprim/sulfamethoxazole (6.7 %). Isolates of S. pseudintermedius showed highest susceptibility to enrofloxacin (81.8 %), followed by cephalexin (79.0 %), gentamycin (77.8 %), tetracyclines (66.7 %), trimethoprim/sulfamethoxazole (62.6 %), amoxicillin/clavulanic acid (54.6 %) and ampicillin (26.3 %). Isolates of E. coli showed highest susceptibility to gentamycin (44.4 %), followed by cephalexin (38.6 %), enrofloxacin (27.8 %), tetracyclines (17.7 %), amoxicillin/clavulanic acid (15.0 %), trimethoprim/sulfamethoxazole (12.5 %), and ampicillin (4.4 %). Results indicate unpredictable antibiotic susceptibility of bacterial isolates, and possible therapeutic failure if empirical therapy is instituted according to the existing guidelines. When possible, antimicrobial therapy should be initiated based on culture and AST results.

Izvorni jezik
Engleski

Znanstvena područja
Veterinarska medicina

POVEZANOST RADA