Tick-borne encephalitis outbreak following raw goat milk consumption in a new micro-location, Croatia, June 2019

Ilic, Maja; Barbić, Ljubo; Bogdanić, Maja; Tabain, Irena; Savić, Vladimir; Kosanović Ličina, Mirjana Lana; Kaić, Bernard; Jungić, Andreja; Vucelja, Marko; Angelov, Vlado; Kovačević, Marinka; Rončević, Dobrica; Knežević, Samira; Stevanović, Vladimir; Slavuljica, Irena; Lakoseljac, Danijela; Vicković, Ninoslava; Bubonja-Sonje, Marina; Hansen, Lisa; Vilibić-Čavlek, Tatjana

doi:10.1016/j.ttbdis.2020.101513

Pregled bibliografske jedinice broj: 1107503

Tick-borne encephalitis outbreak following raw goat milk consumption in a new micro- location, Croatia, June 2019

Ilic, Maja; Barbić, Ljubo; Bogdanić, Maja; Tabain, Irena; Savić, Vladimir; Kosanović Ličina, Mirjana Lana; Kaić, Bernard; Jungić, Andreja; Vucelja, Marko; Angelov, Vlado et al.

Tick-borne encephalitis outbreak following raw goat milk consumption in a new micro- location, Croatia, June 2019 // Ticks and Tick-Borne Diseases, 11 (2020), 6; 101513, 1 doi:10.1016/j.ttbdis.2020.101513 (međunarodna recenzija, kratko priopcenje, znanstveni)

CROSBI ID: 1107503 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Tick-borne encephalitis outbreak following raw goat milk consumption in a new micro- location, Croatia, June 2019

Autori
Ilic, Maja ; Barbić, Ljubo ; Bogdanić, Maja ; Tabain, Irena ; Savić, Vladimir ; Kosanović Ličina, Mirjana Lana ; Kaić, Bernard ; Jungić, Andreja ; Vucelja, Marko ; Angelov, Vlado ; Kovačević, Marinka ; Rončević, Dobrica ; Knežević, Samira ; Stevanović, Vladimir ; Slavuljica, Irena ; Lakoseljac, Danijela ; Vicković, Ninoslava ; Bubonja-Sonje, Marina ; Hansen, Lisa ; Vilibić-Čavlek, Tatjana

Izvornik
Ticks and Tick-Borne Diseases (1877-959X) 11 (2020), 6; 101513, 1

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kratko priopcenje, znanstveni

Ključne riječi
tick-borne encephalitis ; croatia ; goat milk ; one health

Sažetak
In June 2019, the Croatian Institute of Public Health was informed of a cluster of patients with laboratory confirmed tick-borne encephalitis (TBE) from the Gorski Kotar region. Five of the six patients with TBE reported consuming raw (unpasteurized) goat milk in the two week period before symptom onset, and one reported a recent tick bite. To assess risk factors for infection, we selected six control individuals from among healthy family and community members, and conducted a case-control analysis. None of the cases or controls were vaccinated against TBE. Individuals with TBE (cases) had 25 (95 % CI 0.8- 1410.2, p = 0.021) times higher odds of raw goat milk consumption compared to healthy controls. Milk samples from 12 goats from the implicated farm were tested for the TBE virus (TBEV) using RT-PCR. TBEV RNA was not detected in the milk, but serological testing of goats and other farm animals yielded evidence of exposure to the virus: Six goats from the flock had TBEV neutralizing antibodies. Our findings suggest that the vehicle for the outbreak was raw goat milk from a single farm. Following public health advice to cease consumption of raw dairy products, no further cases have been reported.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA

Projekti:
HRZZ-IP-2016-06-7456 - Prevalencija i molekularna epidemiologija emergentnih i re-emergentnih neuroinvazivnih arbovirusnih infekcija na području Hrvatske (CRONEUROARBO) (Vilibić Čavlek, Tatjana, HRZZ - 2016-06) ( CroRIS)

Ustanove:
Hrvatski zavod za javno zdravstvo,
Hrvatski veterinarski institut, Zagreb,
Veterinarski fakultet, Zagreb,
Medicinski fakultet, Rijeka,
Fakultet šumarstva i drvne tehnologije,
Medicinski fakultet, Zagreb,
Nastavni zavod za javno zdravstvo "Dr. Andrija Štampar",
Klinika za infektivne bolesti "Dr Fran Mihaljević",
Klinički bolnički centar Rijeka

Profili:

Marina Bubonja Šonje (autor)