Naslov
Complexes of Azithromycin with Some Divalent Metal Ions

Autori
Đokić, Slobodan ; Vajtner, Zlatko ; Lopotar, Nevenka ; Mrvoš-Sermek, Draginja ; Kamenar, Boris ; Nagl, Ante

Izvornik
Croatica chemica acta (0011-1643) 68 (1995), 2; 375-381

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
azithromycin, metal complexes

Sažetak
The formation of 2 : 1 complexes of azithromycin with copper(II), zinc(II), cobalt(II), nickel(II), magnesium(II) and calcium(II) ions was examined. These compounds (2-7) showed the same in vitro biological potency as azithromycin (1). The complexes (3- 7) are isostructural and different when compared with azithromycin-Cu(II)- complex. Copper(II)-complex (2) was most stable and selected for structure determination by X-ray crystallography. Some physical characteristics and analyses of the complexes are also presented.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Farmacija

POVEZANOST RADA