Naslov
Reporting of over-the-counter drugs adverse drug reactions in 2018.

Autori
Bukić, Josipa ; Kellner, Markus ; Leskur, Dario ; Rušić, Doris ; Šešelja Perišin, Ana ; Mas, Petar ; Margan Koletić, Željana ; Tomić, Siniša ; Modun, Darko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
9. hrvatski kongres farmakologije s međunarodnim sudjelovanjem: zbornik sažetaka / - Zagreb, 2019, 144-144

Skup
9. hrvatski kongres farmakologije = 9th Croatian Congress of Pharmacology

Mjesto i datum
Zagreb, Hrvatska, 25.09.2019. - 28.09.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
OTC drugs ; Pharmacovigilance ; Adverse drug reactions ; Drug safety ; Spontaneous reporting

Sažetak
Introduction: A growing popularity of self-medication process has been acknowledged. This trend could be explained due to the fact that has several advantages for both consumers and health care professionals. However, over-the-counter (OTC) drug use could also result with adverse drug reactions and these reactions should be reported to national authority. Materials and methods: This was a cross sectional study containing data on reported adverse drug reactions from Agency for Medicinal Products and Medical devices of Croatia (HALMED). The Croatian drug database (available online) was searched before requesting HALMED for the data reports. Inclusion criteria for database search was OTC drug, and it consisted of both analgesic and non-analgesic drugs marketed in Croatia. In 2019 overall 466 drugs were registered as OTC drugs, and were included in this study. Adverse drug reaction reports data were analysed: reporter qualification, patient gender and age, seriousness and active substance name. Results: Number of adverse drug reaction reports during the examined period was 165. The adverse drug reactions were most frequently reported by pharmacists, followed by consumers. Fifty-three percent of all reports were classified as serious. Most commonly reported drugs were ibuprofen, paracetamol and Hedera helix. Accidental exposures to products by child was reported in 26 cases of adverse drug reactions. Conclusion: The major risk associated with OTC drug consumption in 2018 was accidental exposure to products by child, and awareness of childproofing mechanisms should be raised.

Izvorni jezik
Engleski

Znanstvena područja
Farmacija

POVEZANOST RADA