Naslov
HudinaEffects of pharmaceutical pollutants on physiology of the invasive signal crayfish, Pacifastacus leniusculus (Dana, 1852)
(Effects of pharmaceutical pollutants on physiology of the invasive signal crayfish, Pacifastacus leniusculus (Dana, 1852))

Autori
Krsnik, Jelena ; Razić, Matea ; Tarandek, Anita ; Radić Brkanac, Sandra ; Blažević, Sofia Ana ; Klobučar, Goran ; Martinović-Weigelt, Dalma ; Hudina, Sandra

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of Abstracts (3rd Symposium of Freshwater Biology) / Ivković, Marija ; Stanković, Igor ; Matoničkin Kepčija, Renata ; Gračan, Romana - Zagreb, 2019, 16-16

Skup
6. simpozij o biologiji slatkih voda (SOBS2019)

Mjesto i datum
Zagreb, Hrvatska, 15.02.2019

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
no keywords

Sažetak
Pharmaceutical pollution in freshwaters can affect behavior and physiology of freshwater organisms since most pharmaceuticals are designed to act quickly in human body and leave the body without degrading, so they enter the freshwaters still pharmacologically active. Recent studies have demonstrated that pharmaceuticals can exhibit effects on behavior and physiology of freshwater organisms in environmentally relevant concentrations. This study explores whether pharmaceuticals commonly present along the Croatian section of the Sava River (antidepressants Citalopram and Nortriptyline, and illicit drug Amphetamine) could have an effect on physiology of the most successful crustacean invader of European freshwaters, Signal crayfish (Pacifastacus leniusculus). We exposed individuals to environmentally relevant (low), or therapeutic (high) concentration of Citalopram, Nortriptyline or Amphetamine dissolved in ambient water for 7 days. Since antidepressants act via alterations in serotogenic metabolism and receptors and since in crayfish serotonin mediates the release of cHH, hormone that controls hemolymph glucose concentration, we chose to measure the following physiological endpoints after 7-day exposure: concentration of serotonin in the brain, concentration of glucose in hemolymph, as well as markers of oxidative stress. We compared the results obtained for exposed individuals to their respective control groups. We did not observe any influence of examined pharmaceuticals on serotonin levels, and in concordance to our expectations exposure to tested concentrations did not exert any oxidative stress upon individuals. We also did not observe significant effects on glucose levels except for Amphetamine where glucose levels were lower than in control group at both concentrations.

Izvorni jezik
Engleski

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