Naslov
Kakvoća biljnog lijeka
(Quality of Herbal Medicinal Products (HMP))

Autori
Cvek, Josipa ; Borić, Ana ; Medić-Šarić ; Marica ; Tomić, Siniša

Izvornik
Farmaceutski glasnik : glasilo Hrvatskog farmaceutskog društva (0014-8202) 62 (2006), 4; 187-204

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
biljni lijekovi, kakvoća, onečišćenja
(herbal medicinal products, quality, impurities)

Sažetak
A lot of factors such as temperature, light exposure, water availabilit y, nutritients, period and site of collection, age and part of plant collected, method of collection, processing (drying, chemical/radioactive treatment, ...), storage and distribution of starting herbal material, etc., can greatly affect the qualit y and consequently the therapeutic value of herbal medicines. Therefore, it is essential to produce starting material under Good Agriculture and Collection Practice (GACP) conditions. Because of plant's genetic and chemical content variations, the site and date should be recorded for each collection. The production of starting materials by cultivation would normally lead to more consistent herbal products due to greater genetic uniformit y. Furthermore, cultivation permits monitoring of active constituents and defining of the best period for harvesting. Whether field collected from the wild or produced by cultivation, botanical authentication of plant species and identification by their binomial Latin names are necessary to insure that the correct herbal material is obtained. Also, care must be taken to free the targeted starting material of undesirable plant parts, soil, insects, animal excreta and other contaminants. During post-collection treatments microbial, agrochemical residues and toxic metals contamination should be reduced to a minimum. The harvested starting material must be processed to produce the finished herbal product under Good Manufacture Practices (GMPs) which are similar to those employed for the manufacture of conventional drugs.

Izvorni jezik
Hrvatski

Znanstvena područja
Farmacija

POVEZANOST RADA