Naslov
BACTERIAL PATHOGENS AND ANTIMICROBIAL SUSCEPTIBILITY PATTERNS IN URINARY TRACT INFECTIONS IN DOGS

Autori
Kajin, Filip ; Torti, Marin ; Šmit, Iva ; Jović, Ines ; Crnogaj, Martina ; Gotić, Jelena ; Brkljačić, Mirna ; Matijatko, Vesna ; Kiš, Ivana ; Tršan, Jurica ; Filipčić, Ivana ; Štritof, Zrinka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of Abstracts of 8th International Congress “Veterinary Science and Profession” / Brkljača-Bottegaro, Nika ; Zdolec, Nevijo ; Vrbanac, Zoran - Zagreb : Veterinarski fakultet Sveučilišta u Zagrebu, 2019, 84-84

ISBN
978-953-8006-24-1

Skup
8. međunarodni kongres Veterinarska znanost i struka

Mjesto i datum
Zagreb, Hrvatska, 10.10.2019. - 12.10.2019

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
urinary tract infections, susceptibility patterns, bacteria, dogs

Sažetak
Bacterial urinary tract inflammation (UTI) is a common cause of morbidity in dogs and among the leading reasons for antimicrobial use. An improper therapy leads to treatment failure and favours the development of antimicrobial resistance. The International Society for Companion Animal Infectious Diseases (ISCAID) provides guidelines and recommendations for the diagnosis and treatment of UTI. Multidrug-resistant (MDR) bacteria, non-susceptible to at least one agent in three or more antimicrobial categories, have become a major challenge in both veterinary and human medicine, thus presenting one of the most important public health issues. The surveillance of local pathogen susceptibility patterns is essential for an optimal empirical therapy. The aim of this retrospective study was to analyse canine urinary tract pathogens and their antimicrobial susceptibility patterns. The study included 275 urine samples obtained from dogs admitted at the Clinic for Internal Diseases of the Faculty of Veterinary Medicine, Zagreb, Croatia, in the period from 1 January 2018 to 1 May 2019. The culture of 192 (70%) urines was negative, while 83 (30%) yielded a significant bacterial growth. The most commonly identified bacteria were: Escherichia coli (41%), Proteus spp. (19%) and Staphylococcus pseudintermedius (10%), with the incidence of MDR among them being 17%, 41% and 44%, respectively. Resistance to one or more β-lactam antibiotics (most notably amoxicillin) was found in 83% of E. coli and 55% of S. pseudintermedius, while 47% of Proteus spp. were resistant to potentiated sulphonamides. These findings raise concern, since those are the first-choice antimicrobials for the treatment of sporadic and recurrent bacterial cystitis as recommended by the ISCAID. This study serves as a reminder that clinicians should be aware of local (ideally clinic-level) antimicrobial susceptibility patterns to help guide empirical choices.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Veterinarska medicina

POVEZANOST RADA